Chemical Component Summary

NameSEROTONIN
Synonyms3-(2-AMINOETHYL)-1H-INDOL-5-OL
Identifiers3-(2-aminoethyl)-1H-indol-5-ol
FormulaC10 H12 N2 O
Molecular Weight176.215
TypeNON-POLYMER
Isomeric SMILESc1cc2c(cc1O)c(c[nH]2)CCN
InChIInChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
InChIKeyQZAYGJVTTNCVMB-UHFFFAOYSA-N

Chemical Details

Formal Charge0
Atom Count25
Chiral Atom Count0
Bond Count26
Aromatic Bond Count10

Drug Info: DrugBank

DrugBank IDDB08839 
NameSerotonin
Groups
  • nutraceutical
  • investigational
DescriptionFor temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
Synonyms
  • 5-Hydroxytryptamine
  • sérotonine
  • 3-(2-Aminoethyl)-1H-indol-5-ol
  • thrombocytin
  • thrombotonin
Categories
  • Amines
  • Antidepressive Agents
  • Autacoids
  • Biogenic Amines
  • Biogenic Monoamines
CAS number50-67-9

Drug Targets

NameTarget SequencePharmacological ActionActions
Sodium-dependent serotonin transporterMETTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAV...unknown
5-hydroxytryptamine receptor 2AMDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSE...unknown
5-hydroxytryptamine receptor 3AMLLWVQQALLALLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVR...unknown
5-hydroxytryptamine receptor 3BMLSSVMAPLWACILVAAGILATDTHHPQDSALYHLSKQLLQKYHKEVRPV...unknown
Synaptic vesicular amine transporterMALSELALVRWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYS...unknown
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL39
PubChem 5202
ChEMBL CHEMBL39
ChEBI CHEBI:28790
CCDC/CSD VIKWIX, SERHOX, SERPIC, JECDII