SAL

2-HYDROXYBENZOIC ACID

Created:1999-07-08
Last modified:  2024-09-27

Find related ligands:

Chemical Details

Formal Charge0
Atom Count16
Chiral Atom Count0
Bond Count16
Aromatic Bond Count6
2D diagram of SAL

Chemical Component Summary

Name2-HYDROXYBENZOIC ACID
SynonymsSALICYLIC ACID
Systematic Name (OpenEye OEToolkits)2-hydroxybenzoic acid
FormulaC7 H6 O3
Molecular Weight138.121
TypeNON-POLYMER

Chemical Descriptors

TypeProgramVersionDescriptor
SMILESACDLabs10.04O=C(O)c1ccccc1O
SMILESCACTVS3.341OC(=O)c1ccccc1O
SMILESOpenEye OEToolkits1.5.0c1ccc(c(c1)C(=O)O)O
Canonical SMILESCACTVS3.341 OC(=O)c1ccccc1O
Canonical SMILESOpenEye OEToolkits1.5.0 c1ccc(c(c1)C(=O)O)O
InChIInChI1.03 InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKeyInChI1.03 YGSDEFSMJLZEOE-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank IDDB00936 
NameSalicylic acid
Groups
  • vet_approved
  • approved
  • investigational
DescriptionA compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Synonyms
  • Salicylic acid
  • ácido salicílico
  • 2-Carboxyphenol
  • 2-Hydroxybenzoic acid
  • Sodium salicylate
Brand Names
  • Ped X Callus Removers, Medicated
  • HAIRNA Care
  • Leahue Madhuca
  • AcNesic Acne Treatment
  • OXY Rapid Treatment 3 in 1 Pads Maximum Action
IndicationKey additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
Categories
  • Acids, Carbocyclic
  • Agents causing hyperkalemia
  • Agents that produce hypertension
  • Analgesics
  • Analgesics, Non-Narcotic
ATC-Code
  • D01AE12
  • G04BX17
  • N02BA04
  • N02BA12
  • S01BC08
CAS number69-72-7

Drug Targets

NameTarget SequencePharmacological ActionActions
Carbonic anhydrase 6MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPI...unknowninhibitor
Carbonic anhydrase 12MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSC...unknowninhibitor
Carbonic anhydrase 2MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS...unknowninhibitor
Carbonic anhydrase 4MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDR...unknowninhibitor
Carbonic anhydrase 1MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISV...unknowninhibitor
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL424
PubChem 338, 118212070
ChEMBL CHEMBL424
ChEBI CHEBI:16914
CCDC/CSD HAGTOY, BUVBIG, BUVBIG02, HUWHAK, KUJDIE, GEYSAE02, EJIFIO, IFEFUX, GOKQUV01, BUVBIG01, DKPSAL10, DOGCAG, LATLAV, CIXMED, GOKQUV, ENICEK, BULKOK, EZEGIA, KOPKEH, LATKUO, HOYXIE, IFEFOR, CEKNEN, KIGLES, GEYSAE, DUPXEU, HOGFEQ, ACETAF, GIHCAD, CARTEW, HUNJIL, KIGLES01, BULJID, DUPXIY, KIJKUL, APYSAL, IZAHEZ, KOPKEH01, CUWFIM, AVEHER, GAHZOI, KOPKEH02, AQEJEO
COD 2100548, 2022076, 4504244, 1519837, 4503560, 7214357, 7208274, 4500305