Chemical Component Summary

NameRETINOL
Identifiers(2~{E},4~{E},6~{E},8~{E})-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol
FormulaC20 H30 O
Molecular Weight286.452
TypeNON-POLYMER
Isomeric SMILESCC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/CO)/C)/C
InChIInChI=1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
InChIKeyFPIPGXGPPPQFEQ-OVSJKPMPSA-N

Chemical Details

Formal Charge0
Atom Count51
Chiral Atom Count0
Bond Count51
Aromatic Bond Count0

Drug Info: DrugBank

DrugBank IDDB00162 
NameVitamin A
Groups
  • approved
  • vet_approved
  • nutraceutical
DescriptionRetinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
Synonyms
  • Vitamin A
  • all-trans-vitamin A alcohol
  • all-trans-retinyl alcohol
  • Vitamin A1
  • Vitamin A palmitate
Brand Names
  • Everyday Multiple Vitamins With Iron
  • Multivitamin with 0.25 mg Fluoride
  • Real Vitamin Supplement Cap
  • Vitamin A Tab 10000unit
  • Multiple Vitamins Childrens Chewable
IndicationFor the treatment of vitamin A deficiency.
Categories
  • Adjuvants, Immunologic
  • Alimentary Tract and Metabolism
  • Alkenes
  • Anti-Acne Preparations
  • Anti-Acne Preparations for Topical Use
ATC-Code
  • S01XA02
  • V04CB01
  • D10AD02
  • R01AX02
  • A11CA01
CAS number68-26-8

Drug Targets

NameTarget SequencePharmacological ActionActions
Apolipoprotein DMVMLLLLLSALAGLFGAAEGQAFHLGKCPNPPVQENFDVNKYLGRWYEIE...unknownligand
Prostaglandin-H2 D-isomeraseMATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLAS...unknownligand
Retinol dehydrogenase 12MLVTLGLLTSFFSFLYMVAPSIRKFFAGGVCRTNVQLPGKVVVITGANTG...unknownsubstrate
11-cis retinol dehydrogenaseMWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLLALQLDQ...unknownsubstrate
Retinol dehydrogenase 13MSRYLLPLSALGTVAGAAVLLKDYVTGGACPSKATIPGKTVIVTGANTGI...unknownsubstrate
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
Pharos CHEMBL986
PubChem 445354
ChEMBL CHEMBL986
ChEBI CHEBI:17336