Chemical Component Summary | |
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Name | MIMOSINE |
Synonyms | 3-HYDROXY-4-OXO-1(4H)-PYRIDINEALANINE |
Identifiers | (2S)-2-amino-3-(3-hydroxy-4-oxo-pyridin-1-yl)propanoic acid |
Formula | C8 H10 N2 O4 |
Molecular Weight | 198.176 |
Type | NON-POLYMER |
Isomeric SMILES | C1=CN(C=C(C1=O)O)C[C@@H](C(=O)O)N |
InChI | InChI=1S/C8H10N2O4/c9-5(8(13)14)3-10-2-1-6(11)7(12)4-10/h1-2,4-5,12H,3,9H2,(H,13,14)/t5-/m0/s1 |
InChIKey | WZNJWVWKTVETCG-YFKPBYRVSA-N |
Chemical Details | |
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Formal Charge | 0 |
Atom Count | 24 |
Chiral Atom Count | 1 |
Bond Count | 24 |
Aromatic Bond Count | 6 |
Drug Info: DrugBank
DrugBank ID | DB01055 |
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Name | Mimosine |
Groups | experimental |
Description | Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from _Leucena glauca_. |
Synonyms |
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Categories |
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CAS number | 500-44-7 |
Drug Targets
Name | Target Sequence | Pharmacological Action | Actions |
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Serine hydroxymethyltransferase, cytosolic | MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLEL... | unknown | inhibitor |
C-C motif chemokine 2 | MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLAS... | unknown | inhibitor |
Tyrosinase | MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLS... | unknown | inhibitor |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
Resource Name | Reference |
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PubChem | 6971294, 440473 |
ChEMBL | CHEMBL245416 |
ChEBI | CHEBI:77689, CHEBI:29063, CHEBI:77848 |