Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma.
Synonyms
1-hydroxy-2-methoxybenzene
Guaiacol hydrochloride
2-methoxyl-4-vinylphenol
o-Methoxyphenol
o-hydroxyanisole
Guaiacol carbonate
Guaiacol
Pyroguaiac acid
o-guaiacol
2-methoxyphenol
Pyrocatechol monomethyl ether
Brand Names
Analgesic Balm
Jamp-suppositories Children
Pastilles Valda
Jamp-cough Suppositories Adult
Demo-cineol Adultes/adults
Valda Pastilles
Valda Pastilles Lemon Flavoured
Creo-rectal Adultes/adults
Dry Socket
Demo Cineol Inj
Creo-rectal Nourrisson
Dentalgar Liq
Creo-rectal Enfants/children
Demo-cineol Enfants/children
Gouttes Dentaires
Indication
It is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a potent scavenger of reactive oxygen radicals and its radical scavenging activity may be associated with its effect on cell proliferation.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
