HSL

HOMOSERINE LACTONE

Created:	2001-11-02
Last modified:	2024-09-27

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2 entries where HSL is found as a standalone ligand8 entries where HSL is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	14
Chiral Atom Count	1
Bond Count	14
Aromatic Bond Count	0

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Chemical Component Summary
Name	HOMOSERINE LACTONE
Systematic Name (OpenEye OEToolkits)	(3S)-3-aminooxolan-2-one
Formula	C₄ H₇ N O₂
Molecular Weight	101.104
Type	L-PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C1OCCC1N
SMILES	CACTVS	3.341	N[CH]1CCOC1=O
SMILES	OpenEye OEToolkits	1.5.0	C1COC(=O)C1N
Canonical SMILES	CACTVS	3.341	N[C@H]1CCOC1=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C1COC(=O)[C@H]1N
InChI	InChI	1.03	InChI=1S/C4H7NO2/c5-3-1-2-7-4(3)6/h3H,1-2,5H2/t3-/m0/s1
InChIKey	InChI	1.03	QJPWUUJVYOJNMH-VKHMYHEASA-N

Drug Info: DrugBank

DrugBank ID	DB02624
Name	Homoserine Lactone
Groups	experimental
Synonyms	Homoserine Lactone
Categories	Furans Lactones Luminescent Proteins
CAS number	1192-20-7

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Sodium/hydrogen exchanger 1	MVLRSGICGLSPHRIFPSLLVVVALVGLLPVLRSHGLQLSPTASTIRSSE...	unknown	inhibitor

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682