Chemical Component Summary | |
|---|---|
| Name | GUANIDINE |
| Identifiers | guanidine |
| Formula | C H5 N3 |
| Molecular Weight | 59.07 |
| Type | NON-POLYMER |
| Isomeric SMILES | C(=N)(N)N |
| InChI | InChI=1S/CH5N3/c2-1(3)4/h(H5,2,3,4) |
| InChIKey | ZRALSGWEFCBTJO-UHFFFAOYSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 9 |
| Chiral Atom Count | 0 |
| Bond Count | 8 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB00536 |
|---|---|
| Name | Guanidine |
| Groups | approved |
| Description | A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC. |
| Synonyms |
|
| Brand Names | Guanidine hydrochloride |
| Indication | For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis. |
| Categories |
|
| CAS number | 113-00-8 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Aldehyde dehydrogenase, mitochondrial | MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVS... | unknown | inhibitor |
| Ribonuclease pancreatic | MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSS... | unknown | |
| DNA | - | unknown | |
| Disks large homolog 4 | MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGY... | unknown | |
| Lysozyme | MNIFEMLRIDERLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAI... | unknown | |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| Pharos | CHEMBL821 |
| PubChem | 3520 |
| ChEMBL | CHEMBL821 |
| ChEBI | CHEBI:42820 |
| CCDC/CSD | AJAPIL01, AJAPIL04, AJAPIL03, AJAPIL02, AJAPIL06, AJAPIL, AJAPIL05 |
| COD | 4507696, 4507697 |
