FMX

FAMOXADONE

Created:	2002-02-25
Last modified:	2020-06-05

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3 entries where FMX is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	46
Chiral Atom Count	1
Bond Count	49
Aromatic Bond Count	18

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Chemical Component Summary
Name	FAMOXADONE
Synonyms	5-METHYL-5-(4-PHENOXYPHENYL)-3-(PHENYLAMINO)-2,4-OXAZOLIDINEDIONE
Systematic Name (OpenEye OEToolkits)	(5S)-5-methyl-5-(4-phenoxyphenyl)-3-phenylazanyl-1,3-oxazolidine-2,4-dione
Formula	C₂₂ H₁₈ N₂ O₄
Molecular Weight	374.389
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C2OC(C(=O)N2Nc1ccccc1)(c4ccc(Oc3ccccc3)cc4)C
SMILES	CACTVS	3.341	C[C]1(OC(=O)N(Nc2ccccc2)C1=O)c3ccc(Oc4ccccc4)cc3
SMILES	OpenEye OEToolkits	1.5.0	CC1(C(=O)N(C(=O)O1)Nc2ccccc2)c3ccc(cc3)Oc4ccccc4
Canonical SMILES	CACTVS	3.341	C[C@]1(OC(=O)N(Nc2ccccc2)C1=O)c3ccc(Oc4ccccc4)cc3
Canonical SMILES	OpenEye OEToolkits	1.5.0	C[C@@]1(C(=O)N(C(=O)O1)Nc2ccccc2)c3ccc(cc3)Oc4ccccc4
InChI	InChI	1.03	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3/t22-/m0/s1
InChIKey	InChI	1.03	PCCSBWNGDMYFCW-QFIPXVFZSA-N

Drug Info: DrugBank

DrugBank ID	DB07778
Name	(S)-famoxadone
Groups	experimental
Synonyms	(S)-(−)-famoxadone (S)-famoxadone (S)-5-Methyl-5-(4-phenoxy-phenyl)-3-phenylamino-oxazolidine-2,4-dione (−)-famoxadone
CAS number	132584-12-4

Drug Targets

Name	Target Sequence	Pharmacological Action
Cytochrome c1, heme protein, mitochondrial	MAAAAASLRGVVLGPRGAGLPGARARGLLCSARPGQLPLRTPQAVALSSK...	unknown
Cytochrome b	MTPMRKTNPLMKLINHSFIDLPTPSNISAWWNFGSLLGACLILQITTGLF...	unknown
Cytochrome b-c1 complex subunit 1, mitochondrial	MAASVVCRAATAGAQVLLRARRSPALLRTPALRSTATFAQALQFVPETQV...	unknown
Cytochrome b-c1 complex subunit 2, mitochondrial	MKLLTRAGSFSRFYSLKVAPKVKATAAPAGAPPQPQDLEFTKLPNGLVIA...	unknown
Cytochrome b-c1 complex subunit 6, mitochondrial	MGLEDEQKMLTESGDPEEEEEEEEELVDPLTTVREQCEQLEKCVKARERL...	unknown
Cytochrome b-c1 complex subunit 8	MGREFGNLTRMRHVISYSLSPFEQRAYPHVFTKGIPNVLRRIRESFFRVV...	unknown
Cytochrome b-c1 complex subunit Rieske, mitochondrial	MLSVASRSGPFAPVLSATSRGVAGALRPLVQATVPATPEQPVLDLKRPFL...	unknown
Cytochrome b-c1 complex subunit 10	MVTRFLGPRYRELVKNWVPTAYTWGAVGAVGLVWATDWRLILDWVPYING...	unknown
Cytochrome b-c1 complex subunit 7	MAGKQAVSASGKWLDGIRKWYYNAAGFNKLGLMRDDTIYEDEDVKEAIRR...	unknown
Cytochrome b-c1 complex subunit 9	MAAATLTSKLYSLLFRRTSTFALTIIVGVMFFERAFDQGADAIYDHINEG...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682