DU

2'-DEOXYURIDINE-5'-MONOPHOSPHATE

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is present as a standalone ligand in 8 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 1 entries

is present in a polymer sequence 117 entries

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Chemical Component Summary
Name	2'-DEOXYURIDINE-5'-MONOPHOSPHATE
Identifiers	[(2R,3S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₉ H₁₃ N₂ O₈ P
Molecular Weight	308.182
Type	DNA LINKING
Isomeric SMILES	C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COP(=O)(O)O)O
InChI	InChI=1S/C9H13N2O8P/c12-5-3-8(11-2-1-7(13)10-9(11)14)19-6(5)4-18-20(15,16)17/h1-2,5-6,8,12H,3-4H2,(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1
InChIKey	JSRLJPSBLDHEIO-SHYZEUOFSA-N

Chemical Details
Formal Charge	0
Atom Count	33
Chiral Atom Count	3
Bond Count	34
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB03800
Name	Deoxyuridine monophosphate
Groups	experimental
Synonyms	Deoxyuridylate 2'-deoxyuridine 5'-monophosphate Deoxyuridine 5'-phosphate Deoxyuridylic acid dUMP 2'-Deoxyuridine 5'-phosphate Deoxyuridine monophosphate
Categories	Deoxyribonucleotides Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Pyrimidine Nucleotides Pyrimidines Uracil Nucleotides
CAS number	964-26-1

Drug Targets

Name	Target Sequence	Pharmacological Action
Deoxyuridine 5'-triphosphate nucleotidohydrolase	MKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELAPGDTTLV...	unknown
Thymidylate synthase	MLEQPYLDLAKKVLDEGHFKPDRTHTGTYSIFGHQMRFDLSKGFPLLTTK...	unknown
Thymidylate synthase	MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRC...	unknown
Thymidylate synthase	MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDR...	unknown
Thymidylate synthase ThyX	MKIDILDKGFVELVDVMGNDLSAVRAARVSFDMGLKDEERDRHLIEYLMK...	unknown
Pol polyprotein	KEFGKLEGGASCSPSESNAASSNAICTSNGGETIGFVNYNKVGTTTTLEK...	unknown
Deoxyuridine 5'-triphosphate nucleotidohydrolase	MSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVA...	unknown
Thymidylate synthase	MVNAEEQQYLNLVQYIINHGEDRPDRTGTGTLSVFAPSPLKFSLRNKTFP...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682