DNE
D-NORLEUCINE
| Created: | 2003-11-14 |
| Last modified: | 2024-09-27 |
Find Related PDB Entry |
|---|
Find related ligands: |
|---|
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 22 |
| Chiral Atom Count | 1 |
| Bond Count | 21 |
| Aromatic Bond Count | 0 |
Chemical Component Summary | |
|---|---|
| Name | D-NORLEUCINE |
| Systematic Name (OpenEye OEToolkits) | (2~{R})-2-azanylhexanoic acid |
| Formula | C6 H13 N O2 |
| Molecular Weight | 131.173 |
| Type | D-PEPTIDE LINKING |
Chemical Descriptors | |||
|---|---|---|---|
| Type | Program | Version | Descriptor |
| SMILES | ACDLabs | 10.04 | O=C(O)C(N)CCCC |
| SMILES | CACTVS | 3.385 | CCCC[CH](N)C(O)=O |
| SMILES | OpenEye OEToolkits | 3.1.0.0 | CCCCC(C(=O)O)N |
| Canonical SMILES | CACTVS | 3.385 | CCCC[C@@H](N)C(O)=O |
| Canonical SMILES | OpenEye OEToolkits | 3.1.0.0 | CCCC[C@H](C(=O)O)N |
| InChI | InChI | 1.03 | InChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m1/s1 |
| InChIKey | InChI | 1.03 | LRQKBLKVPFOOQJ-RXMQYKEDSA-N |
Drug Info: DrugBank
| DrugBank ID | DB04419 |
|---|---|
| Name | D-norleucine |
| Groups | experimental |
| Description | An unnatural amino acid that is used experimentally to study protein structure and function. It is structurally similar to METHIONINE, however it does not contain SULFUR. |
| Synonyms |
|
| CAS number | 327-56-0 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Phenylalanine-4-hydroxylase | MSTAVLENPGLGRKLSDFGQETSYIEDNCNQNGAISLIFSLKEEVGALAK... | unknown | |
| Parathyroid hormone | MIPAKDMAKVMIVMLAICFLTKSDGKSVKKRSVSEIQLMHNLGKHLNSME... | unknown | |
| Hepatocyte nuclear factor 1-alpha | MVSKLSQLQTELLAALLESGLSKEALIQALGEPGPYLLAGEGPLDKGESC... | unknown |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 6999776, 456468 |
| ChEBI | CHEBI:143080, CHEBI:42101 |
| CCDC/CSD | DLNLIT, GOLVOS, GOLVIM01, GOLVIM02, GOLVUY, GOLWAF, GOLVIM, FITLEZ, GOLVIM03, DLNLUA03, ZATPIX, ZATNUH |
| COD | 4509815, 4509813 |
