CGU

GAMMA-CARBOXY-GLUTAMIC ACID

Created:	1999-07-08
Last modified:	2024-09-27

Find Related PDB Entry
84 entries where CGU is found in a polymer sequence

Help Find related ligands:
Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Help

Find related ligands:

Similar Ligands (Stereospecific) Similar Ligands (including Stereoisomers) Similar Ligands (Quick Screen) Similar Ligands (Substructure Stereospecific) Similar Ligands (Substructure including Stereoisomers)

Chemical Details
Formal Charge	0
Atom Count	22
Chiral Atom Count	1
Bond Count	21
Aromatic Bond Count	0

Toggle Hydrogen Toggle Labels

Chemical Component Summary
Name	GAMMA-CARBOXY-GLUTAMIC ACID
Systematic Name (OpenEye OEToolkits)	(3S)-3-aminopropane-1,1,3-tricarboxylic acid
Formula	C₆ H₉ N O₆
Molecular Weight	191.139
Type	L-PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)C(C(=O)O)CC(N)C(=O)O
SMILES	CACTVS	3.341	N[CH](CC(C(O)=O)C(O)=O)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C(C(C(=O)O)C(=O)O)C(C(=O)O)N
Canonical SMILES	CACTVS	3.341	N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C(C(C(=O)O)C(=O)O)[C@@H](C(=O)O)N
InChI	InChI	1.03	InChI=1S/C6H9NO6/c7-3(6(12)13)1-2(4(8)9)5(10)11/h2-3H,1,7H2,(H,8,9)(H,10,11)(H,12,13)/t3-/m0/s1
InChIKey	InChI	1.03	UHBYWPGGCSDKFX-VKHMYHEASA-N

Drug Info: DrugBank

DrugBank ID	DB03847
Name	gamma-carboxy-L-glutamic acid
Groups	experimental
Synonyms	gamma-carboxy-L-glutamic acid (3S)-3-amino-1,1,3-propanetricarboxylic acid gamma-Carboxyglutamic acid γ-carboxy-L-glutamic acid gamma-carboxy-glutamic acid
Categories	1-Carboxyglutamic Acid Acids, Acyclic Amino Acids Amino Acids, Acidic Amino Acids, Dicarboxylic Amino Acids, Peptides, and Proteins Glutamates Tricarboxylic Acids
CAS number	53861-57-7

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Prothrombin	MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEE...	unknown	inhibitor
Coagulation factor IX	MQRVNMIMAESPGLITICLLGYLLSAECTVFLDHENANKILNRPKRYNSG...	unknown	inhibitor
Coagulation factor X	MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKK...	unknown	inhibitor
Osteocalcin	MRALTLLALLALAALCIAGQAGAKPSGAESSKGAAFVSKQEGSEVVKRPR...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682