AP6

2,4-DIAMINO-6-PHENYL-5,6,7,8,-TETRAHYDROPTERIDINE

Created:	1999-12-16
Last modified:	2011-06-04

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1 entries where AP6 is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	32
Chiral Atom Count	1
Bond Count	34
Aromatic Bond Count	12

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Chemical Component Summary
Name	2,4-DIAMINO-6-PHENYL-5,6,7,8,-TETRAHYDROPTERIDINE
Systematic Name (OpenEye OEToolkits)	(6R)-6-phenyl-5,6,7,8-tetrahydropteridine-2,4-diamine
Formula	C₁₂ H₁₄ N₆
Molecular Weight	242.28
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n3c(nc2c(NC(c1ccccc1)CN2)c3N)N
SMILES	CACTVS	3.341	Nc1nc(N)c2N[CH](CNc2n1)c3ccccc3
SMILES	OpenEye OEToolkits	1.5.0	c1ccc(cc1)C2CNc3c(c(nc(n3)N)N)N2
Canonical SMILES	CACTVS	3.341	Nc1nc(N)c2N[C@@H](CNc2n1)c3ccccc3
Canonical SMILES	OpenEye OEToolkits	1.5.0	c1ccc(cc1)[C@@H]2CNc3c(c(nc(n3)N)N)N2
InChI	InChI	1.03	InChI=1S/C12H14N6/c13-10-9-11(18-12(14)17-10)15-6-8(16-9)7-4-2-1-3-5-7/h1-5,8,16H,6H2,(H5,13,14,15,17,18)/t8-/m0/s1
InChIKey	InChI	1.03	VEKRIXRQADJFAG-QMMMGPOBSA-N

Drug Info: DrugBank

DrugBank ID	DB02911
Name	2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine
Groups	experimental
Synonyms	2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Nitric oxide synthase, endothelial	MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAP...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682