7PCL
BurG (holo) in complex with 2-hydroxy-2-(hydroxy(isopropyl)amino)acetate (11): Biosynthesis of cyclopropanolrings in bacterial toxins
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | IlvC | e7pclB2 | A: alpha arrays | X: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology) | H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology) | T: 6-phosphogluconate dehydrogenase C-terminal domain-like | F: IlvC | ECOD (1.6) |
B | IlvN | e7pclB1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: IlvN | ECOD (1.6) |
A | IlvC | e7pclA2 | A: alpha arrays | X: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology) | H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology) | T: 6-phosphogluconate dehydrogenase C-terminal domain-like | F: IlvC | ECOD (1.6) |
A | IlvN | e7pclA1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: IlvN | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF07991 | Acetohydroxy acid isomeroreductase, NADPH-binding domain (IlvN) | Acetohydroxy acid isomeroreductase, NADPH-binding domain | - | Family | |
PF01450 | Acetohydroxy acid isomeroreductase, catalytic domain (IlvC) | Acetohydroxy acid isomeroreductase, catalytic domain | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR015878 | S-adenosyl-L-homocysteine hydrolase, NAD binding domain | Domain | |
IPR013023 | Ketol-acid reductoisomerase | Family | |
IPR036291 | NAD(P)-binding domain superfamily | Homologous Superfamily | |
IPR000506 | Ketol-acid reductoisomerase, C-terminal | Domain | |
IPR013116 | Ketol-acid reductoisomerase, N-terminal | Domain | |
IPR008927 | 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily | Homologous Superfamily |