Annotations: 6X0H

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	K_oxygenase_1	e6x0hA1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: K_oxygenase_1	ECOD (1.6)
A	K_oxygenase	e6x0hA2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: Nucleotide-binding domain	F: K_oxygenase	ECOD (1.6)
C	K_oxygenase_1	e6x0hC1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: K_oxygenase_1	ECOD (1.6)
C	K_oxygenase	e6x0hC2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: Nucleotide-binding domain	F: K_oxygenase	ECOD (1.6)
D	K_oxygenase_1	e6x0hD1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: K_oxygenase_1	ECOD (1.6)
D	K_oxygenase	e6x0hD2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: Nucleotide-binding domain	F: K_oxygenase	ECOD (1.6)
B	K_oxygenase_1	e6x0hB1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: FAD/NAD(P)-binding domain	F: K_oxygenase_1	ECOD (1.6)
B	K_oxygenase	e6x0hB2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: Nucleotide-binding domain	F: K_oxygenase	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF13434	L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase (Lys_Orn_oxgnase)	L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	L-ornithine N(5)-monooxygenase	NADP+ binding binding nucleotide binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding heterocyclic compound binding NADP binding small molecule binding ornithine N5-monooxygenase activity monooxygenase activity NADP+ binding binding nucleotide binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding heterocyclic compound binding NADP binding small molecule binding ornithine N5-monooxygenase activity monooxygenase activity oxidoreductase activity catalytic activity cation binding transition metal ion binding iron ion binding metal ion binding N,N-dimethylaniline monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	intracellular iron ion homeostasis inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis secondary metabolite biosynthetic process biosynthetic process metabolic process cellular process intracellular iron ion homeostasis inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis secondary metabolite biosynthetic process biosynthetic process metabolic process cellular process secondary metabolic process hydroxymate-containing siderophore biosynthetic process amide biosynthetic process ferrichrome metabolic process siderophore biosynthetic process peptide biosynthetic process siderophore metabolic process amide metabolic process nonribosomal peptide biosynthetic process peptide metabolic process ferrichrome biosynthetic process phytosteroid metabolic process secondary alcohol biosynthetic process small molecule biosynthetic process organic hydroxy compound metabolic process steroid metabolic process sterol metabolic process lipid biosynthetic process primary metabolic process alcohol metabolic process ergosterol biosynthetic process phytosteroid biosynthetic process secondary alcohol metabolic process sterol biosynthetic process organic hydroxy compound biosynthetic process alcohol biosynthetic process small molecule metabolic process ergosterol metabolic process steroid biosynthetic process lipid metabolic process cellular response to stimulus response to nutrient levels response to stimulus cellular response to starvation cellular response to iron ion starvation cellular response to nutrient levels cellular response to stress response to stress response to starvation import into cell siderophore-dependent iron import into cell cellular localization iron import into cell transport metal ion transport localization establishment of localization in cell monoatomic ion transport monoatomic cation transport iron ion transport establishment of localization transition metal ion transport iron coordination entity transport	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR025700	L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase	Family
A, B, C, D	IPR036188	FAD/NAD(P)-binding domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.