Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth C]C1-set_4e6b0gC2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
A [auth C]V-sete6b0gC1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
B [auth D]V-set_8e6b0gD2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_8ECOD (1.6)
B [auth D]C1-set_1e6b0gD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
C [auth E]EGF_CAe6b0gE3 A: few secondary structure elementsX: EGF-likeH: EGF-relatedT: EGF/LamininF: EGF_CAECOD (1.6)
C [auth E]Plasmod_Pvs28e6b0gE2 A: few secondary structure elementsX: EGF-likeH: EGF-relatedT: EGF/LamininF: Plasmod_Pvs28ECOD (1.6)
C [auth E]UNK_F_TYPEe6b0gE1 A: few secondary structure elementsX: EGF-likeH: Fibulin-4 EGF-like 1 domain (From Topology)T: Fibulin-4 EGF-like 1 domainF: UNK_F_TYPEECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A [auth C]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
B [auth D]2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)
C [auth E]2.90.20.10 Mainly Beta Orthogonal Prism Plasmodium vivax P25 fold Plasmodium vivax P25 domainCATH (4.3.0)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
A [auth C]Fab 1245 L-KAPPA Homo sapiens (human) IGKV2-30*01, IGKJ4*01, IGKJ4*02, IGKJ1S2*01, IGKC*01 V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA IG FAB-GAMMA-1_KAPPA IMGT (202448-0)
B [auth D]Fab 1245 VH-CH1 Homo sapiens (human) IGHV1-18*01, IGHV1-18*04, IGHJ6*01, IGHJ6*02, IGHG1*01, IGHG1*02, IGHG1*04, IGHG1*05 V-DOMAIN VH, C-DOMAIN CH1 IG FAB-GAMMA-1_KAPPA IMGT (202448-0)

SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
A [auth C]Light ChainIGKV2 Kappa25 kda ookinete surface antigenSAbDab (2024-12-06)
B [auth D]Heavy ChainIGHV1 -25 kda ookinete surface antigenSAbDab (2024-12-06)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
C [auth E]PF06247Pvs28 EGF domain (Plasmod_Pvs28)Pvs28 EGF domainThis family consists of several ookinete surface proteins (Pvs28) from several species of Plasmodium. Pvs25 and Pvs28 are expressed on the surface of ookinetes. These proteins are potential candidates for vaccine and induce antibodies that block the ...This family consists of several ookinete surface proteins (Pvs28) from several species of Plasmodium. Pvs25 and Pvs28 are expressed on the surface of ookinetes. These proteins are potential candidates for vaccine and induce antibodies that block the infectivity of Plasmodium vivax in immunised animals [1]. The structure of this protein shows it is composed of four EGF domains [2].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth C]1245 Antibody, Light Chain---
B [auth D]1245 Antibody, Heavy Chain---
C [auth E]25 kDa ookinete surface antigen- -

InterPro: Protein Family Classification InterPro Database Homepage