Annotations: 6FEA

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Nitrogenase iron-molybdenum protein	8069052	4000849	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Helical backbone metal receptor	8069053	3001679	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	Helical backbone metal receptor	8069053	3001679	SCOP2B (2022-06-29)
B	SCOP2 Family	Nitrogenase iron-molybdenum protein	8076794	4000849	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Helical backbone metal receptor	8076795	3001679	SCOP2 (2022-06-29)
E	SCOP2B Superfamily	Helical backbone metal receptor	8076795	3001679	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	UNK_F_TYPE	e6feaC1	A: alpha arrays	X: Nitrogenase vanadium-iron protein delta chain (From Topology)	H: Nitrogenase vanadium-iron protein delta chain (From Topology)	T: Nitrogenase vanadium-iron protein delta chain	F: UNK_F_TYPE	ECOD (1.6)
F	UNK_F_TYPE	e6feaF1	A: alpha arrays	X: Nitrogenase vanadium-iron protein delta chain (From Topology)	H: Nitrogenase vanadium-iron protein delta chain (From Topology)	T: Nitrogenase vanadium-iron protein delta chain	F: UNK_F_TYPE	ECOD (1.6)
A	Oxidored_nitro_3rd	e6feaA3	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: Oxidored_nitro_3rd	ECOD (1.6)
A	Oxidored_nitro_1st	e6feaA2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: Oxidored_nitro_1st	ECOD (1.6)
A	UNK_F_TYPE	e6feaA1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: UNK_F_TYPE	ECOD (1.6)
D	Oxidored_nitro_3rd	e6feaD3	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: Oxidored_nitro_3rd	ECOD (1.6)
D	Oxidored_nitro_1st	e6feaD1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: Oxidored_nitro_1st	ECOD (1.6)
D	UNK_F_TYPE	e6feaD2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: UNK_F_TYPE	ECOD (1.6)
B	Oxidored_nitro_3rd	e6feaB1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: Oxidored_nitro_3rd	ECOD (1.6)
B	Oxidored_nitro_1st	e6feaB2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: Oxidored_nitro_1st	ECOD (1.6)
B	UNK_F_TYPE	e6feaB3	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: UNK_F_TYPE	ECOD (1.6)
E	Oxidored_nitro_3rd	e6feaE3	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: Oxidored_nitro_3rd	ECOD (1.6)
E	Oxidored_nitro_1st	e6feaE2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: Oxidored_nitro_1st	ECOD (1.6)
E	UNK_F_TYPE	e6feaE1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Class I glutamine amidotransferase-like	T: Chelatase-like	F: UNK_F_TYPE	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.1980	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Nitrogenase molybdenum iron protein domain	CATH (utative)
D	3.40.50.1980	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Nitrogenase molybdenum iron protein domain	CATH (utative)
B	3.40.50.1980	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Nitrogenase molybdenum iron protein domain	CATH (4.3.0)
E	3.40.50.1980	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Nitrogenase molybdenum iron protein domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C, F	PF03139	Vanadium/alternative nitrogenase delta subunit (AnfG_VnfG)	Vanadium/alternative nitrogenase delta subunit	-	Family
A, D	PF00148	Nitrogenase component 1 type Oxidoreductase (Oxidored_nitro)	Nitrogenase component 1 type Oxidoreductase	-	Domain
B, E	PF00148	Nitrogenase component 1 type Oxidoreductase (Oxidored_nitro)	Nitrogenase component 1 type Oxidoreductase	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
C, F	Vanadium nitrogenase, delta subunit, VnfG	iron-sulfur cluster binding binding metal cluster binding small molecule binding cation binding ion binding metal ion binding oxidoreductase activity nitrogenase activity oxidoreductase activity, acting on iron-sulfur proteins as donors catalytic activity oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor	nitrogen cycle metabolic process metabolic process cellular process nitrogen fixation	-
A, D	Nitrogenase protein alpha chain	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding iron-sulfur cluster binding metal cluster binding vanadium ion binding cation binding transition metal ion binding metal ion binding oxidoreductase activity nitrogenase activity oxidoreductase activity, acting on iron-sulfur proteins as donors catalytic activity oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor	nitrogen cycle metabolic process metabolic process cellular process nitrogen fixation	-
B, E	Vanadium nitrogenase beta subunit, vnfK	iron-sulfur cluster binding binding metal cluster binding small molecule binding cation binding ion binding metal ion binding oxidoreductase activity nitrogenase activity oxidoreductase activity, acting on iron-sulfur proteins as donors catalytic activity oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor	nitrogen cycle metabolic process metabolic process cellular process nitrogen fixation	protein-containing complex catalytic complex nitrogenase complex vanadium-iron nitrogenase complex oxidoreductase complex intracellular protein-containing complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C, F	IPR014279	Nitrogenase vanadium-iron, delta subunit	Family
C, F	IPR004349	Vanadium/alternative nitrogenase delta subunit	Family
A, D	IPR000510	Nitrogenase/oxidoreductase, component 1	Domain
A, D	IPR010142	Nitrogenase vanadium-iron protein, alpha chain	Family
A, D	IPR000318	Nitrogenase component 1, conserved site	Conserved Site
A, D	IPR010143	Nitrogenase component 1, alpha chain	Family
A, D	IPR005974	Nitrogenase alpha chain	Family
B, E	IPR000510	Nitrogenase/oxidoreductase, component 1	Domain
B, E	IPR000318	Nitrogenase component 1, conserved site	Conserved Site
B, E	IPR050152	ChlB/BchB/BchZ	Family
B, E	IPR014281	Nitrogenase vanadium-iron protein beta chain	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.