5NWC
Crystal structure of TNKS2 in complex with 2-(2-aminophenyl)-3,4-dihydroquinazolin-4-one
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B [auth H] | PARP | e5nwcH1 | A: a+b complex topology | X: ADP-ribosylation (From Topology) | H: ADP-ribosylation (From Topology) | T: ADP-ribosylation | F: PARP | ECOD (1.6) |
D [auth I] | PARP | e5nwcI1 | A: a+b complex topology | X: ADP-ribosylation (From Topology) | H: ADP-ribosylation (From Topology) | T: ADP-ribosylation | F: PARP | ECOD (1.6) |
A | PARP | e5nwcA1 | A: a+b complex topology | X: ADP-ribosylation (From Topology) | H: ADP-ribosylation (From Topology) | T: ADP-ribosylation | F: PARP | ECOD (1.6) |
C [auth B] | PARP | e5nwcB1 | A: a+b complex topology | X: ADP-ribosylation (From Topology) | H: ADP-ribosylation (From Topology) | T: ADP-ribosylation | F: PARP | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B [auth H] | 6.20.320.10 | Special | Other non-globular | YefM-like fold | CATH (4.3.0) | |
D [auth I] | 6.20.320.10 | Special | Other non-globular | YefM-like fold | CATH (4.3.0) | |
A | 3.90.228.10 | Alpha Beta | Alpha-Beta Complex | Phosphoenolpyruvate Carboxykinase | domain 3 | CATH (4.3.0) |
C [auth B] | 3.90.228.10 | Alpha Beta | Alpha-Beta Complex | Phosphoenolpyruvate Carboxykinase | domain 3 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, C [auth B] | PF00644 | Poly(ADP-ribose) polymerase catalytic domain (PARP) | Poly(ADP-ribose) polymerase catalytic domain | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
B [auth H], D [auth I] | IPR050745 | Multifunctional regulatory proteins | Family |
B [auth H], D [auth I] | IPR036770 | Ankyrin repeat-containing domain superfamily | Homologous Superfamily |
B [auth H], D [auth I] | IPR012317 | Poly(ADP-ribose) polymerase, catalytic domain | Domain |
B [auth H], D [auth I] | IPR002110 | Ankyrin repeat | Repeat |
B [auth H], D [auth I] | IPR013761 | Sterile alpha motif/pointed domain superfamily | Homologous Superfamily |
B [auth H], D [auth I] | IPR001660 | Sterile alpha motif domain | Domain |
A, C [auth B] | IPR050745 | Multifunctional regulatory proteins | Family |
A, C [auth B] | IPR036770 | Ankyrin repeat-containing domain superfamily | Homologous Superfamily |
A, C [auth B] | IPR012317 | Poly(ADP-ribose) polymerase, catalytic domain | Domain |
A, C [auth B] | IPR002110 | Ankyrin repeat | Repeat |
A, C [auth B] | IPR013761 | Sterile alpha motif/pointed domain superfamily | Homologous Superfamily |
A, C [auth B] | IPR001660 | Sterile alpha motif domain | Domain |