Annotations: 5BUP

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	ZP domain-like	8047457	4005646	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Zona pellucida-like domain (ZP domain / ZP-like domain / ZP module)	8052311	3002103	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Zona_pellucida_C	e5bupA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Zona_pellucida_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.40.4100	Mainly Beta	Sandwich	Immunoglobulin-like	Zona pellucida, ZP-C domain	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Zona pellucida sperm-binding protein 2	protein binding binding acrosin binding enzyme binding identical protein binding structural constituent of egg coat structural molecule activity extracellular matrix structural constituent	multicellular organismal process regulation of biological process sexual reproduction regulation of reproductive process reproductive process fertilization egg activation cell activation biological regulation negative regulation of biological process regulation of fertilization negative regulation of fertilization negative regulation of reproductive process prevention of polyspermy multicellular organismal process regulation of biological process sexual reproduction regulation of reproductive process reproductive process fertilization egg activation cell activation biological regulation negative regulation of biological process regulation of fertilization negative regulation of fertilization negative regulation of reproductive process prevention of polyspermy cellular process single fertilization sperm-egg recognition cell-cell recognition binding of sperm to zona pellucida cell recognition	cellular anatomical structure extracellular region cell periphery extracellular matrix external encapsulating structure collagen-containing extracellular matrix egg coat plasma membrane membrane membrane-bounded organelle intracellular anatomical structure endosome intracellular vesicle intracellular membrane-bounded organelle cellular anatomical structure extracellular region cell periphery extracellular matrix external encapsulating structure collagen-containing extracellular matrix egg coat plasma membrane membrane membrane-bounded organelle intracellular anatomical structure endosome intracellular vesicle intracellular membrane-bounded organelle endomembrane system intracellular organelle cytoplasmic vesicle organelle late endosome cytoplasm multivesicular body vesicle endoplasmic reticulum

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR017977	Zona pellucida domain, conserved site	Conserved Site
A	IPR042235	Zona pellucida, ZP-C domain	Homologous Superfamily
A	IPR051148	Zona Pellucida Domain Glycoprotein	Family
A	IPR048290	Zona pellucida domain, chordate-type	Domain
A	IPR001507	Zona pellucida domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.