4NC0

Crystal Structure of TcdA-A2 Bound to A26.8 VHH

External Resource: Annotation


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Bd4nc0b1 All beta proteins Immunoglobulin-like beta-sandwich Immunoglobulin V set domains (antibody variable domain-like) automated matches (Lama glama ) [TaxId: 9844 ], SCOPe (2.08)
Bd4nc0b2 Artifacts Tags Tags Tags C-terminal Tags (Lama glama ) [TaxId: 9844 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ACW_binding_1e4nc0A1 A: beta duplicates or obligate multimersX: beta-hairpin stack (From Topology)H: beta-hairpin stack (From Topology)T: beta-hairpin stackF: CW_binding_1ECOD (1.6)
BV-set_12e4nc0B1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.10.270.10 Mainly Beta Ribbon left handed beta-beta-3-solenoid Cholin BindingCATH (4.3.0)
B2.60.40.10 Mainly Beta Sandwich Immunoglobulin-like ImmunoglobulinsCATH (4.3.0)

IMGT Antibody Annotation IMGT Database Homepage

ChainProtein NameDescriptionOrganism NameGene Allele Name(s)Domain Name(s)Receptor TypeReceptor DescriptionProvenance Source
A26.8 VHH VH Lama glama (llama) IGHV3S1*01, IGHJ4*01 V-DOMAIN VH IG (VH) IMGT (202448-0)

SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
Heavy ChainIGHV1 -cell wall-binding repeat proteinSAbDab (2024-12-06)