Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
ISCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
KSCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
MSCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
OSCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
QSCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
SSCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
USCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
WSCOP2B SuperfamilyInfluenza hemagglutinin domain-like 8094281 3001342 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
JSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
LSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
NSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
PSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
RSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
TSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
VSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)
XSCOP2B SuperfamilyInfluenza hemagglutinin (stalk) 8088048 3001616 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AA [auth c]C1-set_1e4fqrc2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
AA [auth c]V-set_12e4fqrc1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
CA [auth e]C1-set_1e4fqre2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
CA [auth e]V-set_12e4fqre1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
EA [auth g]C1-set_1e4fqrg2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
EA [auth g]V-set_12e4fqrg1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
GA [auth i]C1-set_1e4fqri2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
GA [auth i]V-set_12e4fqri1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
IA [auth k]C1-set_1e4fqrk2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
IA [auth k]V-set_12e4fqrk1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
KA [auth m]C1-set_1e4fqrm2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
KA [auth m]V-set_12e4fqrm1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
MA [auth o]C1-set_1e4fqro2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
MA [auth o]V-set_12e4fqro1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
OA [auth q]C1-set_1e4fqrq2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
OA [auth q]V-set_12e4fqrq1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
QA [auth s]C1-set_1e4fqrs2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
QA [auth s]V-set_12e4fqrs1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
SA [auth u]C1-set_1e4fqru2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
SA [auth u]V-set_12e4fqru1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
UA [auth w]C1-set_1e4fqrw2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
UA [auth w]V-set_12e4fqrw1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
Y [auth a]C1-set_1e4fqra2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_1ECOD (1.6)
Y [auth a]V-set_12e4fqra1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_12ECOD (1.6)
BA [auth d]C1-set_4e4fqrd2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
BA [auth d]V-sete4fqrd1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
DA [auth f]C1-set_4e4fqrf2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
DA [auth f]V-sete4fqrf1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
FA [auth h]C1-set_4e4fqrh2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
FA [auth h]V-sete4fqrh1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
HA [auth j]C1-set_4e4fqrj2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
HA [auth j]V-sete4fqrj1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
JA [auth l]C1-set_4e4fqrl2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
JA [auth l]V-sete4fqrl1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
LA [auth n]C1-set_4e4fqrn2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
LA [auth n]V-sete4fqrn1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
NA [auth p]C1-set_4e4fqrp2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
NA [auth p]V-sete4fqrp1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
PA [auth r]C1-set_4e4fqrr2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
PA [auth r]V-sete4fqrr1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
RA [auth t]C1-set_4e4fqrt2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
RA [auth t]V-sete4fqrt1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
TA [auth v]C1-set_4e4fqrv2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
TA [auth v]V-sete4fqrv1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
VA [auth x]C1-set_4e4fqrx4 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
VA [auth x]V-sete4fqrx1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
Z [auth b]C1-set_4e4fqrb2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_4ECOD (1.6)
Z [auth b]V-sete4fqrb1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-setECOD (1.6)
AHemagglutinin_1ste4fqrA1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
CHemagglutinin_1ste4fqrC1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
EHemagglutinin_1ste4fqrE1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
GHemagglutinin_1ste4fqrG1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
IHemagglutinin_1ste4fqrI1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
KHemagglutinin_1ste4fqrK1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
MHemagglutinin_1ste4fqrM1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
OHemagglutinin_1ste4fqrO1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
QHemagglutinin_1ste4fqrQ1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
SHemagglutinin_1ste4fqrS1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
UHemagglutinin_1ste4fqrU1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)
WHemagglutinin_1ste4fqrW1 A: beta sandwichesX: jelly-rollH: Viral protein domain (From Topology)T: Viral protein domainF: Hemagglutinin_1stECOD (1.6)

SAbDab Antibody Annotation SAbDab Database Homepage

ChainChain ClassChain SubclassChain TypeAntigen Name(s) Provenance Source
Heavy ChainIGHV3 -broadly neutralizing antibody c05, heavy chainSAbDab (2024-11-15)
Light ChainIGKV1 Kappabroadly neutralizing antibody c05, heavy chainSAbDab (2024-11-15)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, C, E, G, I
PF00509Haemagglutinin (Hemagglutinin)Haemagglutinin- Family
B, D, F, H, J
PF00509Haemagglutinin (Hemagglutinin)Haemagglutinin- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Broadly neutralizing antibody C05, heavy chain---
Broadly neutralizing antibody C05, light chain---
A, C, E, G, I
Hemagglutinin HA1 chain
B, D, F, H, J
Hemagglutinin HA2 chain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, C, E, G, I
IPR001364Haemagglutinin, influenzavirus A/BFamily
A, C, E, G, I
IPR008980Viral capsid/haemagglutinin proteinHomologous Superfamily
A, C, E, G, I
IPR000149Haemagglutinin, influenzavirus AFamily
A, C, E, G, I
IPR013828Haemagglutinin, HA1 chain, alpha/beta domain superfamilyHomologous Superfamily
B, D, F, H, J
IPR001364Haemagglutinin, influenzavirus A/BFamily
B, D, F, H, J
IPR008980Viral capsid/haemagglutinin proteinHomologous Superfamily
B, D, F, H, J
IPR000149Haemagglutinin, influenzavirus AFamily
B, D, F, H, J
IPR013828Haemagglutinin, HA1 chain, alpha/beta domain superfamilyHomologous Superfamily

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
PCA Parent Component: GLN

RESIDAA0031

PSI-MOD :  2-pyrrolidone-5-carboxylic acid (Gln) MOD:00040 , 2-pyrrolidone-5-carboxylic acid (Glu) MOD:00420