3LAJ
The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-arginine.
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | ArgR regulatory domain-like | 8064286 | 3000096 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | ArgR regulatory domain-like | 8064286 | 3000096 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | ArgR regulatory domain-like | 8064286 | 3000096 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | ArgR regulatory domain-like | 8064286 | 3000096 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | ArgR regulatory domain-like | 8064286 | 3000096 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | ArgR regulatory domain-like | 8064286 | 3000096 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Arg_repressor | e3lajA1 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: Arg_repressor | ECOD (1.6) |
A | Arg_repressor_C | e3lajA3 | A: a+b two layers | X: Glucose permease domain IIB-like | H: arginine repressor C terminal domain-related | T: C-terminal domain of arginine repressor | F: Arg_repressor_C | ECOD (1.6) |
B | Arg_repressor | e3lajB1 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: Arg_repressor | ECOD (1.6) |
B | Arg_repressor_C | e3lajB3 | A: a+b two layers | X: Glucose permease domain IIB-like | H: arginine repressor C terminal domain-related | T: C-terminal domain of arginine repressor | F: Arg_repressor_C | ECOD (1.6) |
C | Arg_repressor | e3lajC1 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: Arg_repressor | ECOD (1.6) |
C | Arg_repressor_C | e3lajC3 | A: a+b two layers | X: Glucose permease domain IIB-like | H: arginine repressor C terminal domain-related | T: C-terminal domain of arginine repressor | F: Arg_repressor_C | ECOD (1.6) |
D | Arg_repressor | e3lajD5 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: Arg_repressor | ECOD (1.6) |
D | Arg_repressor_C | e3lajD6 | A: a+b two layers | X: Glucose permease domain IIB-like | H: arginine repressor C terminal domain-related | T: C-terminal domain of arginine repressor | F: Arg_repressor_C | ECOD (1.6) |
E | Arg_repressor | e3lajE5 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: Arg_repressor | ECOD (1.6) |
E | Arg_repressor_C | e3lajE6 | A: a+b two layers | X: Glucose permease domain IIB-like | H: arginine repressor C terminal domain-related | T: C-terminal domain of arginine repressor | F: Arg_repressor_C | ECOD (1.6) |
F | Arg_repressor | e3lajF5 | A: alpha arrays | X: HTH | H: HTH | T: winged | F: Arg_repressor | ECOD (1.6) |
F | Arg_repressor_C | e3lajF6 | A: a+b two layers | X: Glucose permease domain IIB-like | H: arginine repressor C terminal domain-related | T: C-terminal domain of arginine repressor | F: Arg_repressor_C | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01316 | Arginine repressor, DNA binding domain (Arg_repressor) | Arginine repressor, DNA binding domain | - | Domain | |
PF02863 | Arginine repressor, C-terminal domain (Arg_repressor_C) | Arginine repressor, C-terminal domain | This is the C-terminal domain of the arginine repressor, responsible for arginine binding and multimerization [1,2]. It binds mainly Arg, but also ornithine, Pro and Tyr (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.o ... | Domain | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR036388 | Winged helix-like DNA-binding domain superfamily | Homologous Superfamily | |
IPR001669 | Arginine repressor | Family | |
IPR020899 | Arginine repressor, C-terminal | Domain | |
IPR036390 | Winged helix DNA-binding domain superfamily | Homologous Superfamily | |
IPR020900 | Arginine repressor, DNA-binding domain | Domain | |
IPR036251 | Arginine repressor, C-terminal domain superfamily | Homologous Superfamily |