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Crystal Structure of catalytically inactive H270A virginiamycin B lyase from Staphylococcus aureus with Quinupristin External Resource: Annotation Chains Family Name Domain Identifier Architecture Possible Homology Homology Topology Family Provenance Source (Version) B Lactonase_1 e2z2pB1 A: beta duplicates or obligate multimers X: beta-propeller-like H: beta-propeller T: 7-bladed F: Lactonase_1 ECOD (1.6) A Lactonase_1 e2z2pA1 A: beta duplicates or obligate multimers X: beta-propeller-like H: beta-propeller T: 7-bladed F: Lactonase_1 ECOD (1.6)
Chains Accession Short Name Description Provenance Source (Version) ARO:3001307 vgbA vgbA inactivates streptogramin B-type antibiotics by linearizing the lactone ring on the ester bond using an elimination mechanism, thus conferring resistance to these compounds. CARD (3.3.0)
Chains Accession Gene Family Drug Class Resistance Machanism Provenance Source (Version) ARO:3000376 streptogramin vgb lyase streptogramin antibiotic, streptogramin B antibiotic antibiotic inactivation CARD (3.3.0)
Chains Polymer Molecular Function Biological Process Cellular Component Virginiamycin B lyase Quinupristin - - -
Protein Modification Annotation