2RSL | pdb_00002rsl

REFINEMENT OF GAMMA DELTA RESOLVASE REVEALS A STRIKINGLY FLEXIBLE MOLECULE

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d2rslb_	Alpha and beta proteins (a/b)	Resolvase-like	Resolvase-like	gamma,delta resolvase, catalytic domain	gamma,delta resolvase, catalytic domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
C	d2rslc_	Alpha and beta proteins (a/b)	Resolvase-like	Resolvase-like	gamma,delta resolvase, catalytic domain	gamma,delta resolvase, catalytic domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
A	d2rsla_	Alpha and beta proteins (a/b)	Resolvase-like	Resolvase-like	gamma,delta resolvase, catalytic domain	gamma,delta resolvase, catalytic domain	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Resolvase-like	8003596	3000065	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Resolvase-like	8003596	3000065	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Resolvase-like	8003596	3000065	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	Resolvase	e2rslB1	A: a/b three-layered sandwiches	X: Resolvase-like (From Topology)	H: Resolvase-like (From Topology)	T: Resolvase-like	F: Resolvase	ECOD (1.6)
C	Resolvase	e2rslC1	A: a/b three-layered sandwiches	X: Resolvase-like (From Topology)	H: Resolvase-like (From Topology)	T: Resolvase-like	F: Resolvase	ECOD (1.6)
A	Resolvase	e2rslA1	A: a/b three-layered sandwiches	X: Resolvase-like (From Topology)	H: Resolvase-like (From Topology)	T: Resolvase-like	F: Resolvase	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.50.1390	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Resolvase, N-terminal catalytic domain	CATH (4.3.0)
C	3.40.50.1390	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Resolvase, N-terminal catalytic domain	CATH (4.3.0)
A	3.40.50.1390	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Resolvase, N-terminal catalytic domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF00239	Resolvase, N terminal domain (Resolvase)	Resolvase, N terminal domain	The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase - see Pfam:PF02796.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	GAMMA DELTA-RESOLVASE	DNA binding binding nucleic acid binding catalytic activity, acting on DNA catalytic activity, acting on a nucleic acid DNA strand exchange activity catalytic activity	nucleobase-containing compound metabolic process metabolic process cellular process primary metabolic process DNA metabolic process macromolecule metabolic process DNA integration nucleic acid metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR009057	Homedomain-like superfamily	Homologous Superfamily
A, B, C	IPR036162	Resolvase-like, N-terminal catalytic domain superfamily	Homologous Superfamily
A, B, C	IPR006118	Recombinase, conserved site	Conserved Site
A, B, C	IPR006119	Resolvase, N-terminal catalytic domain	Domain
A, B, C	IPR006120	Resolvase, HTH domain	Domain
A, B, C	IPR050639	Site-specific recombinase resolvase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.