2MFC | pdb_00002mfc

Csr/Rsm protein-RNA recognition - A molecular affinity ruler: RsmZ(SL1)/RsmE(dimer) 2:1 complex

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2mfca_	All beta proteins	CsrA-like	CsrA-like	CsrA-like	automated matches	(Pseudomonas fluorescens ) [TaxId: 294 ],	SCOPe (2.08)
C	d2mfcc_	All beta proteins	CsrA-like	CsrA-like	CsrA-like	automated matches	(Pseudomonas fluorescens ) [TaxId: 294 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	CsrA-like	8066756	3000276	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	CsrA-like	8066756	3000276	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	CsrA	e2mfcA1	A: beta duplicates or obligate multimers	X: CsrA-like (From Topology)	H: CsrA-like (From Topology)	T: CsrA-like	F: CsrA	ECOD (1.6)
C	CsrA	e2mfcC1	A: beta duplicates or obligate multimers	X: CsrA-like (From Topology)	H: CsrA-like (From Topology)	T: CsrA-like	F: CsrA	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF02599	Global regulator protein family (CsrA)	Global regulator protein family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	Carbon storage regulator homolog	RNA binding mRNA 5'-UTR binding binding nucleic acid binding mRNA binding	regulation of cellular process negative regulation of biological process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation negative regulation of cellular process translational initiation protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process regulation of translational initiation regulation of protein metabolic process regulation of cellular process negative regulation of biological process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation negative regulation of cellular process translational initiation protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process regulation of translational initiation regulation of protein metabolic process negative regulation of metabolic process biological regulation negative regulation of translational initiation primary metabolic process regulation of macromolecule metabolic process gene expression translation macromolecule biosynthetic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process regulation of translation negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process carbohydrate metabolic process regulation of carbohydrate metabolic process positive regulation of protein metabolic process positive regulation of biological process positive regulation of translation positive regulation of macromolecule biosynthetic process positive regulation of metabolic process positive regulation of biosynthetic process positive regulation of macromolecule metabolic process positive regulation of cellular process positive regulation of gene expression positive regulation of translational initiation catabolic process RNA metabolic process macromolecule catabolic process nucleobase-containing compound metabolic process RNA catabolic process mRNA catabolic process mRNA metabolic process nucleic acid metabolic process nucleobase-containing compound catabolic process nucleic acid catabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol
B, D	SL1(RsmZ) RNA	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR036107	Carbon storage regulator superfamily	Homologous Superfamily
A, C	IPR003751	Translational regulator CsrA	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.