2JGD
E. COLI 2-oxoglutarate dehydrogenase (E1o)
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | Thiamin diphosphate-binding fold (THDP-binding) | 8093314 | 3001790 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | TK C-terminal domain-like | 8093311 | 3000424 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Thiamin diphosphate-binding fold (THDP-binding) | 8093315 | 3001790 | SCOP2B (2022-06-29) |
A | SCOP2 Family | 2-oxoglutarate dehydrogenase C-terminal domain-like | 8046277 | 4004996 | SCOP2 (2022-06-29) |
A | SCOP2 Family | Branched-chain alpha-keto acid dehydrogenase PP module | 8093312 | 4003592 | SCOP2 (2022-06-29) |
A | SCOP2 Family | TK-like Pyr module | 8093313 | 4003561 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | TK C-terminal domain-like | 8093311 | 3000424 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | Thiamin diphosphate-binding fold (THDP-binding) | 8093314 | 3001790 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | Thiamin diphosphate-binding fold (THDP-binding) | 8093315 | 3001790 | SCOP2 (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | OxoGdeHyase_C | e2jgdB1 | A: a/b three-layered sandwiches | X: TK C-terminal domain-like (From Topology) | H: TK C-terminal domain-like (From Topology) | T: TK C-terminal domain-like | F: OxoGdeHyase_C | ECOD (1.6) |
B | E1_dh | e2jgdB3 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: E1_dh | ECOD (1.6) |
B | Transket_pyr | e2jgdB2 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: Transket_pyr | ECOD (1.6) |
A | OxoGdeHyase_C | e2jgdA3 | A: a/b three-layered sandwiches | X: TK C-terminal domain-like (From Topology) | H: TK C-terminal domain-like (From Topology) | T: TK C-terminal domain-like | F: OxoGdeHyase_C | ECOD (1.6) |
A | E1_dh | e2jgdA1 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: E1_dh | ECOD (1.6) |
A | Transket_pyr | e2jgdA2 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: Transket_pyr | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 1.10.287.1150 | Mainly Alpha | Orthogonal Bundle | Helix Hairpins | TPP helical domain | CATH (4.3.0) |
B | 3.40.50.970 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | CATH (4.3.0) |
B | 3.40.50.12470 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
B | 3.40.50.11610 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain | CATH (4.3.0) |
A | 1.10.287.1150 | Mainly Alpha | Orthogonal Bundle | Helix Hairpins | TPP helical domain | CATH (4.3.0) |
A | 3.40.50.970 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | CATH (4.3.0) |
A | 3.40.50.12470 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
A | 3.40.50.11610 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF02779 | Transketolase, pyrimidine binding domain (Transket_pyr) | Transketolase, pyrimidine binding domain | This family includes transketolase enzymes, pyruvate dehydrogenases, and branched chain alpha-keto acid decarboxylases. | Domain | |
PF16870 | 2-oxoglutarate dehydrogenase C-terminal (OxoGdeHyase_C) | 2-oxoglutarate dehydrogenase C-terminal | - | Family | |
PF00676 | Dehydrogenase E1 component (E1_dh) | Dehydrogenase E1 component | - | Family | |
PF02779 | Transketolase, pyrimidine binding domain (Transket_pyr) | Transketolase, pyrimidine binding domain | This family includes transketolase enzymes, pyruvate dehydrogenases, and branched chain alpha-keto acid decarboxylases. | Domain | |
PF16870 | 2-oxoglutarate dehydrogenase C-terminal (OxoGdeHyase_C) | 2-oxoglutarate dehydrogenase C-terminal | - | Family | |
PF00676 | Dehydrogenase E1 component (E1_dh) | Dehydrogenase E1 component | - | Family |