2HMO
Crystal Structure of Naphthalene 1,2-Dioxygenase Bound to 3-Nitrotoluene.
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d2hmob_ | Alpha and beta proteins (a+b) | Cystatin-like | NTF2-like | Ring hydroxylating beta subunit | Naphthalene 1,2-dioxygenase beta subunit | (Pseudomonas sp. ) [TaxId: 306 ], | SCOPe (2.08) |
A | d2hmoa1 | All beta proteins | ISP domain | ISP domain | Ring hydroxylating alpha subunit ISP domain | Naphthalene 1,2-dioxygenase alpha subunit, N-domain | (Pseudomonas sp. ) [TaxId: 306 ], | SCOPe (2.08) |
A | d2hmoa2 | Alpha and beta proteins (a+b) | TBP-like | Bet v1-like | Ring hydroxylating alpha subunit catalytic domain | Naphthalene 1,2-dioxygenase alpha subunit, C-domain | (Pseudomonas sp. ) [TaxId: 306 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | Ring_hydroxyl_B | e2hmoB1 | A: a+b two layers | X: Cystatin-like | H: NTF2-like (From Topology) | T: NTF2-like | F: Ring_hydroxyl_B | ECOD (1.6) |
A | Rieske_5 | e2hmoA1 | A: beta sandwiches | X: ISP domain (From Topology) | H: ISP domain (From Topology) | T: ISP domain | F: Rieske_5 | ECOD (1.6) |
A | Ring_hydroxyl_A | e2hmoA2 | A: a+b two layers | X: TBP-like | H: Bet v1-like (From Topology) | T: Bet v1-like | F: Ring_hydroxyl_A | ECOD (1.6) |
A | Rieske_1 | e2hmoA3 | A: few secondary structure elements | X: Trm112p-like (From Topology) | H: Trm112p-like (From Topology) | T: Trm112p-like | F: Rieske_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.10.450.50 | Alpha Beta | Roll | Nuclear Transport Factor 2 | Chain: A, | CATH (4.3.0) |
A | 3.90.380.10 | Alpha Beta | Alpha-Beta Complex | Naphthalene 1,2-dioxygenase Alpha Subunit | Chain A, domain 1 | CATH (4.3.0) |
A | 2.102.10.10 | Mainly Beta | 3-layer Sandwich | Rieske Iron-sulfur Protein | Rieske [2Fe-2S] iron-sulphur domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00866 | Ring hydroxylating beta subunit (Ring_hydroxyl_B) | Ring hydroxylating beta subunit | This subunit has a similar structure to NTF-2 and scytalone dehydratase. | Domain | |
PF00848 | Ring hydroxylating alpha subunit (catalytic domain) (Ring_hydroxyl_A) | Ring hydroxylating alpha subunit (catalytic domain) | This family is the catalytic domain of aromatic-ring- hydroxylating dioxygenase systems. The active site contains a non-heme ferrous ion coordinated by three ligands. | Domain | |
PF00355 | Rieske [2Fe-2S] domain (Rieske) | Rieske [2Fe-2S] domain | The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in ... | Domain |