2DSY

Crystal structure of TTHA0281 from thermus thermophilus HB8

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
C	d2dsyc_	Alpha and beta proteins (a+b)	TTHA1013/TTHA0281-like	TTHA1013/TTHA0281-like	TTHA0281-like	automated matches	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
A	d2dsya1	Alpha and beta proteins (a+b)	TTHA1013/TTHA0281-like	TTHA1013/TTHA0281-like	TTHA0281-like	Hypothetical protein TTHA0281	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
B	d2dsyb_	Alpha and beta proteins (a+b)	TTHA1013/TTHA0281-like	TTHA1013/TTHA0281-like	TTHA0281-like	automated matches	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)
D	d2dsyd_	Alpha and beta proteins (a+b)	TTHA1013/TTHA0281-like	TTHA1013/TTHA0281-like	TTHA0281-like	automated matches	(Thermus thermophilus ) [TaxId: 274 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2B Superfamily	TTHA1013/TTHA0281-like	8033797	3000880	SCOP2B (2022-06-29)
A	SCOP2 Family	TTHA0281-like	8021417	4001747	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	TTHA1013/TTHA0281-like	8033797	3000880	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	TTHA1013/TTHA0281-like	8033797	3000880	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	TTHA1013/TTHA0281-like	8033797	3000880	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	HicB_lk_antitox_N	e2dsyC1	A: a+b duplicates or obligate multimers	X: TTHA1013/TTHA0281-like (From Topology)	H: TTHA1013/TTHA0281-like (From Topology)	T: TTHA1013/TTHA0281-like	F: HicB_lk_antitox_N	ECOD (1.6)
A	HicB_lk_antitox_N	e2dsyA1	A: a+b duplicates or obligate multimers	X: TTHA1013/TTHA0281-like (From Topology)	H: TTHA1013/TTHA0281-like (From Topology)	T: TTHA1013/TTHA0281-like	F: HicB_lk_antitox_N	ECOD (1.6)
B	HicB_lk_antitox_N	e2dsyB1	A: a+b duplicates or obligate multimers	X: TTHA1013/TTHA0281-like (From Topology)	H: TTHA1013/TTHA0281-like (From Topology)	T: TTHA1013/TTHA0281-like	F: HicB_lk_antitox_N	ECOD (1.6)
D	HicB_lk_antitox_N	e2dsyD1	A: a+b duplicates or obligate multimers	X: TTHA1013/TTHA0281-like (From Topology)	H: TTHA1013/TTHA0281-like (From Topology)	T: TTHA1013/TTHA0281-like	F: HicB_lk_antitox_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	3.30.160.250	Alpha Beta	2-Layer Sandwich	Double Stranded RNA Binding Domain		CATH (4.3.0)
A	3.30.160.250	Alpha Beta	2-Layer Sandwich	Double Stranded RNA Binding Domain		CATH (4.3.0)
B	3.30.160.250	Alpha Beta	2-Layer Sandwich	Double Stranded RNA Binding Domain		CATH (4.3.0)
D	3.30.160.250	Alpha Beta	2-Layer Sandwich	Double Stranded RNA Binding Domain		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF21748	UPF0150-like (UPF0150)	UPF0150-like	This is a family of uncharacterized proteins that fold into an alpha-beta-beta-beta-alpha fold and are structurally similar to HicB-like antitoxin. They are probably involved in RNA metabolism, RNA cleavage and binding [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Hypothetical protein TTHA0281	cation binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR035069	TTHA1013/TTHA0281-like	Homologous Superfamily
A, B, C, D	IPR049389	TTHA0281-like	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.