1ZAX

Ribosomal Protein L10-L12(NTD) Complex, Space Group P212121, Form B

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1zaxa1	Alpha and beta proteins (a+b)	Ferredoxin-like	Ribosomal protein L10-like	Ribosomal protein L10-like	Ribosomal protein L10	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
E [auth X]	d1zaxx1	All alpha proteins	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
B [auth U]	d1zaxu1	All alpha proteins	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
C [auth V]	d1zaxv1	All alpha proteins	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
D [auth W]	d1zaxw1	All alpha proteins	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
F [auth Y]	d1zaxy1	All alpha proteins	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
G [auth Z]	d1zaxz1	All alpha proteins	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Ribosomal protein L10-like	8033487	3000665	SCOP2B (2022-06-29)
E [auth X]	SCOP2B Superfamily	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	8033488	3001092	SCOP2B (2022-06-29)
B [auth U]	SCOP2B Superfamily	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	8033488	3001092	SCOP2B (2022-06-29)
C [auth V]	SCOP2B Superfamily	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	8033488	3001092	SCOP2B (2022-06-29)
D [auth W]	SCOP2B Superfamily	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	8033488	3001092	SCOP2B (2022-06-29)
F [auth Y]	SCOP2B Superfamily	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	8033488	3001092	SCOP2B (2022-06-29)
G [auth Z]	SCOP2B Superfamily	Ribosomal protein L7/12, oligomerisation (N-terminal) domain	8033488	3001092	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Ribosomal_L10	e1zaxA1	A: a+b two layers	X: Alpha-beta plaits	H: Ribosomal protein L10-like (From Topology)	T: Ribosomal protein L10-like	F: Ribosomal_L10	ECOD (1.6)
E [auth X]	Ribosomal_L12_N_2	e1zaxX1	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: Ribosomal_L12_N_2	ECOD (1.6)
B [auth U]	Ribosomal_L12_N_2	e1zaxU1	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: Ribosomal_L12_N_2	ECOD (1.6)
C [auth V]	Ribosomal_L12_N_2	e1zaxV1	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: Ribosomal_L12_N_2	ECOD (1.6)
D [auth W]	Ribosomal_L12_N_2	e1zaxW1	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: Ribosomal_L12_N_2	ECOD (1.6)
F [auth Y]	Ribosomal_L12_N_2	e1zaxY1	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: Ribosomal_L12_N_2	ECOD (1.6)
G [auth Z]	Ribosomal_L12_N_2	e1zaxZ1	A: alpha duplicates or obligate multimers	X: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	H: Ribosomal protein L7/12, oligomerisation (N-terminal) domain (From Topology)	T: Ribosomal protein L7/12, oligomerisation (N-terminal) domain	F: Ribosomal_L12_N_2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.70.1730	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Ribosomal protein L10, N-terminal RNA-binding domain	CATH (4.3.0)
A	6.10.250.290	Special	Helix non-globular	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], G [auth Z]	PF16320	Ribosomal protein L7/L12 dimerisation domain (Ribosomal_L12_N)	Ribosomal protein L7/L12 dimerisation domain	This is the N-terminal dimerisation domain of ribosomal protein L7/L12 [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	50S ribosomal protein L10	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], G [auth Z]	50S ribosomal protein L7/L12	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR043141	Large ribosomal subunit protein uL10-like domain superfamily	Homologous Superfamily
A	IPR001790	Large ribosomal subunit protein uL10	Family
A	IPR047865	Large ribosomal subunit protein uL10, bacterial type	Family
A	IPR022973	Large ribosomal subunit protein uL10, bacterial	Family
A	IPR002363	Large ribosomal subunit protein uL10, conserved site, bacteria	Conserved Site
B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], G [auth Z]	IPR008932	Large ribosomal subunit protein bL12, oligomerization	Domain
B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], G [auth Z]	IPR013823	Large ribosomal subunit protein bL12, C-terminal	Domain
B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], G [auth Z]	IPR036235	Large ribosomal subunit protein bL12, oligomerization domain superfamily	Homologous Superfamily
B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], G [auth Z]	IPR014719	Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like	Homologous Superfamily
B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], B [auth U], C [auth V], D [auth W], E [auth X], F [auth Y], G [auth Z]	IPR000206	Large ribosomal subunit protein bL12	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.