1VZ8

Ornithine Acetyltransferase (ORF6 Gene Product - Clavulanic Acid Biosynthesis) from Streptomyces clavuligerus (SeMet structure)

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1vz8a_	Alpha and beta proteins (a+b)	DmpA/ArgJ-like	DmpA/ArgJ-like	ArgJ-like	Glutamate N-acetyltransferase 2 (ornithine acetyltransferase)	(Streptomyces clavuligerus ) [TaxId: 1901 ],	SCOPe (2.08)
C	d1vz8c_	Alpha and beta proteins (a+b)	DmpA/ArgJ-like	DmpA/ArgJ-like	ArgJ-like	Glutamate N-acetyltransferase 2 (ornithine acetyltransferase)	(Streptomyces clavuligerus ) [TaxId: 1901 ],	SCOPe (2.08)
D	d1vz8d_	Alpha and beta proteins (a+b)	DmpA/ArgJ-like	DmpA/ArgJ-like	ArgJ-like	Glutamate N-acetyltransferase 2 (ornithine acetyltransferase)	(Streptomyces clavuligerus ) [TaxId: 1901 ],	SCOPe (2.08)
B	d1vz8b_	Alpha and beta proteins (a+b)	DmpA/ArgJ-like	DmpA/ArgJ-like	ArgJ-like	Glutamate N-acetyltransferase 2 (ornithine acetyltransferase)	(Streptomyces clavuligerus ) [TaxId: 1901 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	DmpA/ArgJ-like	8041565	3001033	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	DmpA/ArgJ-like	8053798	3001033	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	ArgJ, C-terminal domain	8053799	3002225	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	DmpA/ArgJ-like	8041565	3001033	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	ArgJ, C-terminal domain	8053799	3002225	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	DmpA/ArgJ-like	8053798	3001033	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	ArgJ, C-terminal domain	8053799	3002225	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	DmpA/ArgJ-like	8041565	3001033	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	DmpA/ArgJ-like	8053798	3001033	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	DmpA/ArgJ-like	8053798	3001033	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	DmpA/ArgJ-like	8041565	3001033	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ArgJ, C-terminal domain	8053799	3002225	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	ArgJ_N	e1vz8A1	A: a+b two layers	X: MocoBD/DmpA-related (From Homology)	H: MocoBD/DmpA-related	T: DmpA/ArgJ	F: ArgJ_N	ECOD (1.6)
A	ArgJ_C	e1vz8A2	A: a+b two layers	X: C-terminal domain of OAT (ornithine acetyltransferase) (From Topology)	H: C-terminal domain of OAT (ornithine acetyltransferase) (From Topology)	T: C-terminal domain of OAT (ornithine acetyltransferase)	F: ArgJ_C	ECOD (1.6)
C	ArgJ_N	e1vz8C1	A: a+b two layers	X: MocoBD/DmpA-related (From Homology)	H: MocoBD/DmpA-related	T: DmpA/ArgJ	F: ArgJ_N	ECOD (1.6)
C	ArgJ_C	e1vz8C2	A: a+b two layers	X: C-terminal domain of OAT (ornithine acetyltransferase) (From Topology)	H: C-terminal domain of OAT (ornithine acetyltransferase) (From Topology)	T: C-terminal domain of OAT (ornithine acetyltransferase)	F: ArgJ_C	ECOD (1.6)
D	ArgJ_N	e1vz8D1	A: a+b two layers	X: MocoBD/DmpA-related (From Homology)	H: MocoBD/DmpA-related	T: DmpA/ArgJ	F: ArgJ_N	ECOD (1.6)
D	ArgJ_C	e1vz8D2	A: a+b two layers	X: C-terminal domain of OAT (ornithine acetyltransferase) (From Topology)	H: C-terminal domain of OAT (ornithine acetyltransferase) (From Topology)	T: C-terminal domain of OAT (ornithine acetyltransferase)	F: ArgJ_C	ECOD (1.6)
B	ArgJ_N	e1vz8B1	A: a+b two layers	X: MocoBD/DmpA-related (From Homology)	H: MocoBD/DmpA-related	T: DmpA/ArgJ	F: ArgJ_N	ECOD (1.6)
B	ArgJ_C	e1vz8B2	A: a+b two layers	X: C-terminal domain of OAT (ornithine acetyltransferase) (From Topology)	H: C-terminal domain of OAT (ornithine acetyltransferase) (From Topology)	T: C-terminal domain of OAT (ornithine acetyltransferase)	F: ArgJ_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.60.70.12	Alpha Beta	4-Layer Sandwich	L-amino peptidase D-ALA esterase/amidase	L-amino peptidase D-ALA esterase/amidase	CATH (4.3.0)
A	3.10.20.340	Alpha Beta	Roll	Ubiquitin-like (UB roll)	ArgJ beta chain, C-terminal domain	CATH (4.3.0)
C	3.60.70.12	Alpha Beta	4-Layer Sandwich	L-amino peptidase D-ALA esterase/amidase	L-amino peptidase D-ALA esterase/amidase	CATH (4.3.0)
C	3.10.20.340	Alpha Beta	Roll	Ubiquitin-like (UB roll)	ArgJ beta chain, C-terminal domain	CATH (4.3.0)
D	3.60.70.12	Alpha Beta	4-Layer Sandwich	L-amino peptidase D-ALA esterase/amidase	L-amino peptidase D-ALA esterase/amidase	CATH (4.3.0)
D	3.10.20.340	Alpha Beta	Roll	Ubiquitin-like (UB roll)	ArgJ beta chain, C-terminal domain	CATH (4.3.0)
B	3.60.70.12	Alpha Beta	4-Layer Sandwich	L-amino peptidase D-ALA esterase/amidase	L-amino peptidase D-ALA esterase/amidase	CATH (4.3.0)
B	3.10.20.340	Alpha Beta	Roll	Ubiquitin-like (UB roll)	ArgJ beta chain, C-terminal domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF01960	ArgJ family (ArgJ)	ArgJ family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	ORNITHINE ACETYL-TRANSFERASE	glutamate N-acetyltransferase activity acetyltransferase activity N-acetyltransferase activity acyltransferase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity catalytic activity N-acyltransferase activity L-glutamate N-acetyltransferase activity	L-arginine biosynthetic process oxoacid metabolic process glutamine family amino acid biosynthetic process amino acid metabolic process organic acid metabolic process organic acid biosynthetic process alpha-amino acid metabolic process carboxylic acid biosynthetic process glutamine family amino acid metabolic process arginine metabolic process small molecule metabolic process small molecule biosynthetic process carboxylic acid metabolic process primary metabolic process L-arginine biosynthetic process oxoacid metabolic process glutamine family amino acid biosynthetic process amino acid metabolic process organic acid metabolic process organic acid biosynthetic process alpha-amino acid metabolic process carboxylic acid biosynthetic process glutamine family amino acid metabolic process arginine metabolic process small molecule metabolic process small molecule biosynthetic process carboxylic acid metabolic process primary metabolic process L-amino acid biosynthetic process L-amino acid metabolic process proteinogenic amino acid metabolic process amino acid biosynthetic process biosynthetic process proteinogenic amino acid biosynthetic process metabolic process cellular process alpha-amino acid biosynthetic process ornithine metabolic process ornithine biosynthetic process non-proteinogenic amino acid metabolic process non-proteinogenic amino acid biosynthetic process clavulanic acid biosynthetic process monocarboxylic acid biosynthetic process amide biosynthetic process clavulanic acid metabolic process lactam biosynthetic process lactam metabolic process monocarboxylic acid metabolic process amide metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR002813	Arginine biosynthesis protein ArgJ	Family
A, B, C, D	IPR042195	ArgJ beta chain, C-terminal domain	Homologous Superfamily
A, B, C, D	IPR016117	ArgJ-like domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.