Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1k25a1 Alpha and beta proteins (a+b) Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Ad1k25a3 Alpha and beta proteins (a+b) Penicillin binding protein dimerisation domain Penicillin binding protein dimerisation domain Penicillin binding protein dimerisation domain Penicillin-binding protein 2x (pbp-2x), N-terminal domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Ad1k25a4 Multi-domain proteins (alpha and beta) beta-lactamase/transpeptidase-like beta-lactamase/transpeptidase-like beta-Lactamase/D-ala carboxypeptidase Penicillin-binding protein 2x (pbp-2x), transpeptidase domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Cd1k25c1 Alpha and beta proteins (a+b) Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Cd1k25c3 Alpha and beta proteins (a+b) Penicillin binding protein dimerisation domain Penicillin binding protein dimerisation domain Penicillin binding protein dimerisation domain Penicillin-binding protein 2x (pbp-2x), N-terminal domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Cd1k25c4 Multi-domain proteins (alpha and beta) beta-lactamase/transpeptidase-like beta-lactamase/transpeptidase-like beta-Lactamase/D-ala carboxypeptidase Penicillin-binding protein 2x (pbp-2x), transpeptidase domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Dd1k25d1 Alpha and beta proteins (a+b) Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Dd1k25d3 Alpha and beta proteins (a+b) Penicillin binding protein dimerisation domain Penicillin binding protein dimerisation domain Penicillin binding protein dimerisation domain Penicillin-binding protein 2x (pbp-2x), N-terminal domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Dd1k25d4 Multi-domain proteins (alpha and beta) beta-lactamase/transpeptidase-like beta-lactamase/transpeptidase-like beta-Lactamase/D-ala carboxypeptidase Penicillin-binding protein 2x (pbp-2x), transpeptidase domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Bd1k25b1 Alpha and beta proteins (a+b) Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain Penicillin-binding protein 2x (pbp-2x), c-terminal domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Bd1k25b3 Alpha and beta proteins (a+b) Penicillin binding protein dimerisation domain Penicillin binding protein dimerisation domain Penicillin binding protein dimerisation domain Penicillin-binding protein 2x (pbp-2x), N-terminal domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)
Bd1k25b4 Multi-domain proteins (alpha and beta) beta-lactamase/transpeptidase-like beta-lactamase/transpeptidase-like beta-Lactamase/D-ala carboxypeptidase Penicillin-binding protein 2x (pbp-2x), transpeptidase domain (Streptococcus pneumoniae ) [TaxId: 1313 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APBP_dimere1k25A1 A: beta complex topologyX: Penicillin binding protein dimerisation domain (From Topology)H: Penicillin binding protein dimerisation domain (From Topology)T: Penicillin binding protein dimerisation domainF: PBP_dimerECOD (1.6)
ATranspeptidase_1st_1e1k25A3 A: alpha complex topologyX: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: alpha-helical domain in beta-lactamase/transpeptidase-like proteinsF: Transpeptidase_1st_1ECOD (1.6)
APASTA_2e1k25A5 A: a+b two layersX: CI-2 family of serine protease inhibitors-likeH: Penicillin-binding protein 2x (pbp-2x)-C (From Topology)T: Penicillin-binding protein 2x (pbp-2x)-CF: PASTA_2ECOD (1.6)
APASTA_1e1k25A4 A: a+b two layersX: CI-2 family of serine protease inhibitors-likeH: Penicillin-binding protein 2x (pbp-2x)-C (From Topology)T: Penicillin-binding protein 2x (pbp-2x)-CF: PASTA_1ECOD (1.6)
ATranspeptidase_2nde1k25A2 A: a+b three layersX: Profilin-likeH: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: a+b domain in beta-lactamase/transpeptidase-like proteinsF: Transpeptidase_2ndECOD (1.6)
CPBP_dimere1k25C8 A: beta complex topologyX: Penicillin binding protein dimerisation domain (From Topology)H: Penicillin binding protein dimerisation domain (From Topology)T: Penicillin binding protein dimerisation domainF: PBP_dimerECOD (1.6)
CTranspeptidase_1st_1e1k25C9 A: alpha complex topologyX: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: alpha-helical domain in beta-lactamase/transpeptidase-like proteinsF: Transpeptidase_1st_1ECOD (1.6)
CPASTA_2e1k25C11 A: a+b two layersX: CI-2 family of serine protease inhibitors-likeH: Penicillin-binding protein 2x (pbp-2x)-C (From Topology)T: Penicillin-binding protein 2x (pbp-2x)-CF: PASTA_2ECOD (1.6)
CPASTA_1e1k25C10 A: a+b two layersX: CI-2 family of serine protease inhibitors-likeH: Penicillin-binding protein 2x (pbp-2x)-C (From Topology)T: Penicillin-binding protein 2x (pbp-2x)-CF: PASTA_1ECOD (1.6)
CTranspeptidase_2nde1k25C12 A: a+b three layersX: Profilin-likeH: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: a+b domain in beta-lactamase/transpeptidase-like proteinsF: Transpeptidase_2ndECOD (1.6)
DPBP_dimere1k25D1 A: beta complex topologyX: Penicillin binding protein dimerisation domain (From Topology)H: Penicillin binding protein dimerisation domain (From Topology)T: Penicillin binding protein dimerisation domainF: PBP_dimerECOD (1.6)
DTranspeptidase_1st_1e1k25D6 A: alpha complex topologyX: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: alpha-helical domain in beta-lactamase/transpeptidase-like proteinsF: Transpeptidase_1st_1ECOD (1.6)
DPASTA_2e1k25D5 A: a+b two layersX: CI-2 family of serine protease inhibitors-likeH: Penicillin-binding protein 2x (pbp-2x)-C (From Topology)T: Penicillin-binding protein 2x (pbp-2x)-CF: PASTA_2ECOD (1.6)
DPASTA_1e1k25D3 A: a+b two layersX: CI-2 family of serine protease inhibitors-likeH: Penicillin-binding protein 2x (pbp-2x)-C (From Topology)T: Penicillin-binding protein 2x (pbp-2x)-CF: PASTA_1ECOD (1.6)
DPBP_2x_ClpSe1k25D2 A: a+b two layersX: ClpS-likeH: Penicillin binding protein ClpS-like domain (From Topology)T: Penicillin binding protein ClpS-like domainF: PBP_2x_ClpSECOD (1.6)
DTranspeptidase_2nde1k25D4 A: a+b three layersX: Profilin-likeH: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: a+b domain in beta-lactamase/transpeptidase-like proteinsF: Transpeptidase_2ndECOD (1.6)
BPBP_dimere1k25B1 A: beta complex topologyX: Penicillin binding protein dimerisation domain (From Topology)H: Penicillin binding protein dimerisation domain (From Topology)T: Penicillin binding protein dimerisation domainF: PBP_dimerECOD (1.6)
BTranspeptidase_1st_1e1k25B2 A: alpha complex topologyX: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: alpha-helical domain in beta-lactamase/transpeptidase-like proteinsF: Transpeptidase_1st_1ECOD (1.6)
BPASTA_2e1k25B4 A: a+b two layersX: CI-2 family of serine protease inhibitors-likeH: Penicillin-binding protein 2x (pbp-2x)-C (From Topology)T: Penicillin-binding protein 2x (pbp-2x)-CF: PASTA_2ECOD (1.6)
BPASTA_1e1k25B5 A: a+b two layersX: CI-2 family of serine protease inhibitors-likeH: Penicillin-binding protein 2x (pbp-2x)-C (From Topology)T: Penicillin-binding protein 2x (pbp-2x)-CF: PASTA_1ECOD (1.6)
BPBP_2x_ClpSe1k25B3 A: a+b two layersX: ClpS-likeH: Penicillin binding protein ClpS-like domain (From Topology)T: Penicillin binding protein ClpS-like domainF: PBP_2x_ClpSECOD (1.6)
BTranspeptidase_2nde1k25B6 A: a+b three layersX: Profilin-likeH: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: a+b domain in beta-lactamase/transpeptidase-like proteinsF: Transpeptidase_2ndECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF03717Penicillin-binding Protein dimerisation domain (PBP_dimer)Penicillin-binding Protein dimerisation domainThis domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerisation. The domain forms a largely disordered 'sugar tongs' st ...This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerisation. The domain forms a largely disordered 'sugar tongs' structure.
Domain
A, B, C, D
PF00905Penicillin binding protein transpeptidase domain (Transpeptidase)Penicillin binding protein transpeptidase domainThe active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.Domain
A, B, C, D
PF03793PASTA domain (PASTA)PASTA domainThis domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases [1]. It binds the beta-lactam stem, which implicates it in sensing D-alanyl-D-alanine - the PBP transpeptidase substrate. It is a smal ...This domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases [1]. It binds the beta-lactam stem, which implicates it in sensing D-alanyl-D-alanine - the PBP transpeptidase substrate. It is a small globular fold consisting of 3 beta-sheets and an alpha-helix. The name PASTA is derived from PBP and Serine/Threonine kinase Associated domain.
Domain