1GPW
Structural evidence for ammonia tunneling across the (beta/alpha)8 barrel of the imidazole glycerol phosphate synthase bienzyme complex.
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | Class I glutamine amidotransferase-like | 8037966 | 3001405 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | Class I glutamine amidotransferase-like | 8037966 | 3001405 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | Class I glutamine amidotransferase-like | 8037966 | 3001405 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Ribulose-phoshate binding barrel | 8043236 | 3000216 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Ribulose-phoshate binding barrel | 8043236 | 3000216 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | Ribulose-phoshate binding barrel | 8043236 | 3000216 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | GATase | e1gpwB1 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: Class I glutamine amidotransferase-like | F: GATase | ECOD (1.6) |
D | GATase | e1gpwD1 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: Class I glutamine amidotransferase-like | F: GATase | ECOD (1.6) |
F | GATase | e1gpwF1 | A: a/b three-layered sandwiches | X: Flavodoxin-like | H: Class I glutamine amidotransferase-like | T: Class I glutamine amidotransferase-like | F: GATase | ECOD (1.6) |
A | His_biosynth | e1gpwA1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: His_biosynth | ECOD (1.6) |
C | His_biosynth | e1gpwC1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: His_biosynth | ECOD (1.6) |
E | His_biosynth | e1gpwE1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: His_biosynth | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.40.50.880 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Class I glutamine amidotransferase (GATase) domain | CATH (4.3.0) |
D | 3.40.50.880 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Class I glutamine amidotransferase (GATase) domain | CATH (4.3.0) |
F | 3.40.50.880 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Class I glutamine amidotransferase (GATase) domain | CATH (4.3.0) |
A | 3.20.20.70 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Aldolase class I | CATH (4.3.0) |
C | 3.20.20.70 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Aldolase class I | CATH (4.3.0) |
E | 3.20.20.70 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Aldolase class I | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00117 | Glutamine amidotransferase class-I (GATase) | Glutamine amidotransferase class-I | - | Domain | |
PF07685 | CobB/CobQ-like glutamine amidotransferase domain (GATase_3) | CobB/CobQ-like glutamine amidotransferase domain | - | Domain | |
PF00977 | Histidine biosynthesis protein (His_biosynth) | Histidine biosynthesis protein | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR029062 | Class I glutamine amidotransferase-like | Homologous Superfamily | |
IPR017926 | Glutamine amidotransferase | Domain | |
IPR010139 | Imidazole glycerol phosphate synthase, subunit H | Family | |
IPR011060 | Ribulose-phosphate binding barrel | Homologous Superfamily | |
IPR004651 | Histidine biosynthesis, HisF | Family | |
IPR050064 | Imidazole glycerol phosphate synthase HisA/HisF | Family | |
IPR013785 | Aldolase-type TIM barrel | Homologous Superfamily | |
IPR006062 | Histidine biosynthesis protein | Family |