Potent long-acting inhibitors targeting HIV-1 capsid based on a versatile quinazolin-4-one scaffold

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RCSB PDB Mol* Viewer 2.11.2 [1/27/2025, 4:56:27 PM]
Sequence of
     ​M​​P​​I​​V​​Q​​N​​L​​Q​​G​​Q​10   ​M​​V​​H​​Q​​C​​I​​S​​P​​R​​T​20   ​L​​N​​A​​W​​V​​K​​V​​V​​E​​E​30   ​K​​A​​F​​S​​P​​E​​V​​I​​P​​M​40   ​F​​S​​A​​L​​S​​C​​G​​A​​T​​P​50   ​Q​​D​​L​​N​​T​​M​​L​​N​​T​​V​60   ​G​​G​​H​​Q​​A​​A​​M​​Q​​M​​L​70   ​K​​E​​T​​I​​N​​E​​E​​A​​A​​E​80   ​W​​D​​R​​L​​H​​P​​V​​H​​A​​G​90   ​P​​I​​A​​P​​G​​Q​​M​​R​​E​​P​100  ​R​​G​​S​​D​​I​​A​​G​​T​​T​​S​110  ​T​​L​​Q​​E​​Q​​I​​G​​W​​M​​T​120  ​H​​N​​P​​P​​I​​P​​V​​G​​E​​I​130  ​Y​​K​​R​​W​​I​​I​​L​​G​​L​​N​140  ​K​​I​​V​​R​​M​​Y​​S​​P​​T​​S​150  ​I​​L​​D​​I​​R​​Q​​G​​P​​K​​E​160  ​P​​F​​R​​D​​Y​​V​​D​​R​​F​​Y​170  ​K​​T​​L​​R​​A​​E​​Q​​A​​S​​Q​180  ​E​​V​​K​​N​​A​​A​​T​​E​​T​​L​190  ​L​​V​​Q​​N​​A​​N​​P​​D​​C​​K​200  ​T​​I​​L​​K​​A​​L​​G​​P​​G​​A​210  ​T​​L​​E​​E​​M​​M​​T​​A​​C​​Q​     ​G​​V​​G​​G​​P​​G​​H​​K​​A​​R​     ​V​​L​
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