Crystal structure of the first bromodomain (BD1) of human BRD4 in complex with dual BRD4-JAK2 inhibitor MA9-086

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RCSB PDB Mol* Viewer 2.11.2 [1/27/2025, 4:56:27 PM]
Sequence of
43   ​M​​N​​P​​P​​P​​P​​E​​T​​S​​N​53   ​P​​N​​K​​P​​K​​R​​Q​​T​​N​​Q​63   ​L​​Q​​Y​​L​​L​​R​​V​​V​​L​​K​73   ​T​​L​​W​​K​​H​​Q​​F​​A​​W​​P​83   ​F​​Q​​Q​​P​​V​​D​​A​​V​​K​​L​93   ​N​​L​​P​​D​​Y​​Y​​K​​I​​I​​K​103  ​T​​P​​M​​D​​M​​G​​T​​I​​K​​K​113  ​R​​L​​E​​N​​N​​Y​​Y​​W​​N​​A​123  ​Q​​E​​C​​I​​Q​​D​​F​​N​​T​​M​133  ​F​​T​​N​​C​​Y​​I​​Y​​N​​K​​P​143  ​G​​D​​D​​I​​V​​L​​M​​A​​E​​A​153  ​L​​E​​K​​L​​F​​L​​Q​​K​​I​​N​163  ​E​​L​​P​​T​​E​​E​
Type
Asm Id
Dynamic Bonds

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