Structure of human G9a SET-domain (EHMT2) in complex with inhibitor 17: N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine

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RCSB PDB Mol* Viewer 2.11.1 [12/17/2024, 1:59:56 PM]
Sequence of
     ​T​​R​​T​​E​​K​​I​​I​​C​​R​​D​926  ​V​​A​​R​​G​​Y​​E​​N​​V​​P​​I​936  ​P​​C​​V​​N​​G​​V​​D​​G​​E​​P​946  ​C​​P​​E​​D​​Y​​K​​Y​​I​​S​​E​956  ​N​​C​​E​​T​​S​​T​​M​​N​​I​​D​966  ​R​​N​​I​​T​​H​​L​​Q​​H​​C​​T​976  ​C​​V​​D​​D​​C​​S​​S​​S​​N​​C​986  ​L​​C​​G​​Q​​L​​S​​I​​R​​C​​W​996  ​Y​​D​​K​​D​​G​​R​​L​​L​​Q​​E​1006 ​F​​N​​K​​I​​E​​P​​P​​L​​I​​F​1016 ​E​​C​​N​​Q​​A​​C​​S​​C​​W​​R​1026 ​N​​C​​K​​N​​R​​V​​V​​Q​​S​​G​1036 ​I​​K​​V​​R​​L​​Q​​L​​Y​​R​​T​1046 ​A​​K​​M​​G​​W​​G​​V​​R​​A​​L​1056 ​Q​​T​​I​​P​​Q​​G​​T​​F​​I​​C​1066 ​E​​Y​​V​​G​​E​​L​​I​​S​​D​​A​1076 ​E​​A​​D​​V​​R​​E​​D​​D​​S​​Y​1086 ​L​​F​​D​​L​​D​​N​​K​​D​​G​​E​1096 ​V​​Y​​C​​I​​D​​A​​R​​Y​​Y​​G​1106 ​N​​I​​S​​R​​F​​I​​N​​H​​L​​C​1116 ​D​​P​​N​​I​​I​​P​​V​​R​​V​​F​1126 ​M​​L​​H​​Q​​D​​L​​R​​F​​P​​R​1136 ​I​​A​​F​​F​​S​​S​​R​​D​​I​​R​1146 ​T​​G​​E​​E​​L​​G​​F​​D​​Y​​G​1156 ​D​​R​​F​​W​​D​​I​​K​​S​​K​​Y​1166 ​F​​T​​C​​Q​​C​​G​​S​​E​​K​​C​1176 ​K​​H​​S​​A​​E​​A​​I​​A​​L​​E​1186 ​Q​​S​​R​​L​​A​
Type
Asm Id
Dynamic Bonds

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