4P7E | pdb_00004p7e

Triazolopyridine compounds as selective JAK1 inhibitors: from hit identification to GLPG0634

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RCSB PDB Mol* Viewer 2.11.4 [4/4/2025, 6:48:47 PM]
Sequence of
840  ​D​​P​​T​​Q​​F​​E​​E​​R​​H​​L​850  ​K​​F​​L​​Q​​Q​​L​​G​​K​​G​​N​860  ​F​​G​​S​​V​​E​​M​​C​​R​​Y​​D​870  ​P​​L​​Q​​D​​N​​T​​G​​E​​V​​V​880  ​A​​V​​K​​K​​L​​Q​​H​​S​​T​​E​890  ​E​​H​​L​​R​​D​​F​​E​​R​​E​​I​900  ​E​​I​​L​​K​​S​​L​​Q​​H​​D​​N​910  ​I​​V​​K​​Y​​K​​G​​V​​C​​Y​​S​     ​A​​G​​R​​R​​N​​L​​K​​L​​I​​M​930  ​E​​Y​​L​​P​​Y​​G​​S​​L​​R​​D​940  ​Y​​L​​Q​​K​​H​​K​​E​​R​​I​​D​950  ​H​​I​​K​​L​​L​​Q​​Y​​T​​S​​Q​960  ​I​​C​​K​​G​​M​​E​​Y​​L​​G​​T​970  ​K​​R​​Y​​I​​H​​R​​D​​L​​A​​T​980  ​R​​N​​I​​L​​V​​E​​N​​E​​N​​R​990  ​V​​K​​I​​G​​D​​F​​G​​L​​T​​K​1000 ​V​​L​​P​​Q​​D​​K​​E​​PTR​​PTR​​K​1010 ​V​​K​​E​​P​​G​​E​​S​​P​​I​​F​1020 ​W​​Y​​A​​P​​E​​S​​L​​T​​E​​S​1030 ​K​​F​​S​​V​​A​​S​​D​​V​​W​​S​1040 ​F​​G​​V​​V​​L​​Y​​E​​L​​F​​T​1050 ​Y​​I​​E​​K​​S​​K​​S​​P​​P​​A​1060 ​E​​F​​M​​R​​M​​I​​G​​N​​D​​K​     ​Q​​G​​Q​​M​​I​​V​​F​​H​​L​​I​1080 ​E​​L​​L​​K​​N​​N​​G​​R​​L​​P​1090 ​R​​P​​D​​G​​C​​P​​D​​E​​I​​Y​1100 ​M​​I​​M​​T​​E​​C​​W​​N​​N​​N​1110 ​V​​N​​Q​​R​​P​​S​​F​​R​​D​​L​1120 ​A​​L​​R​​V​​D​​Q​​I​​R​​D​​Q​1130 ​M​​A​​G​
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Asm Id
Dynamic Bonds

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