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4ER0
Crystal Structure of human DOT1L in complex with inhibitor FED1
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RCSB PDB Mol* Viewer 2.11.1 [12/17/2024, 1:59:56 PM]
Sequence of
GMGEKLELRL10 KSPVGAEPAV20 YPWPLPVYDK30 HHDAAHEIIE40 TIRWVCEEIP50 DLKLAMENYV LIDYDTKSFE70 SMQRLCDKYN80 RAIDSIHQLW90 KGTTQPMKLN100 TRPSTGLLRH110 ILQQVYNHSV120 TDPEKLNNYE PFSPEVYGET140 SFDLVAQMID150 EIKMTDDDLF160 VDLGSGVGQV170 VLQVAAATNC180 KHHYGVEKAD190 IPAKYAETMD200 REFRKWMKWY210 GKKHAEYTLE220 RGDFLSEEWR230 ERIANTSVIF240 VNNFAFGPEV250 DHQLKERFAN260 MKEGGRIVSS270 KPFAPLNFRI280 NSRNLSDIGT290 IMRVVELSPL300 KGSVSWTGKP310 VSYYLHTIDR320 TILENYFSSL330 KNPKLREEQE AARRRQQRES KSNAATPTKG PEGKVAGPAD APMDSGAEEE KAGAATVKKP SPSKARKKKL NKKGRKMAGR KRGRPKKMNT A
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Dynamic Bonds
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