Crystal Structure of JAK3 Kinase Domain in Complex with a Pyrrolopyrazine-2-phenyl Ether Inhibitor

WebGL does not seem to be available.

This can be caused by an outdated browser, graphics card driver issue, or bad weather. Sometimes, just restarting the browser helps. Also, make sure hardware acceleration is enabled in your browser.

For a list of supported browsers, refer to http://caniuse.com/#feat=webgl.

Welcome
RCSB PDB Mol* Viewer 2.11.4 [4/4/2025, 6:48:47 PM]
Sequence of
     ​D​​P​​T​​I​​F​​E​​E​​R​​H​​L​823  ​K​​Y​​I​​S​​Q​​L​​G​​K​​G​​N​833  ​F​​G​​S​​V​​E​​L​​C​​R​​Y​​D​843  ​P​​L​​G​​D​​N​​T​​G​​A​​L​​V​853  ​A​​V​​K​​Q​​L​​Q​​H​​S​​G​​P​863  ​D​​Q​​Q​​R​​D​​F​​Q​​R​​E​​I​873  ​Q​​I​​L​​K​​A​​L​​H​​S​​D​​F​883  ​I​​V​​K​​Y​​R​​G​​V​​S​​Y​​G​     ​P​​G​​R​​Q​​S​​L​​R​​L​​V​​M​903  ​E​​Y​​L​​P​​S​​G​​C​​L​​R​​D​913  ​F​​L​​Q​​R​​H​​R​​A​​R​​L​​D​923  ​A​​S​​R​​L​​L​​L​​Y​​S​​S​​Q​933  ​I​​C​​K​​G​​M​​E​​Y​​L​​G​​S​943  ​R​​R​​C​​V​​H​​R​​D​​L​​A​​A​953  ​R​​N​​I​​L​​V​​E​​S​​E​​A​​H​963  ​V​​K​​I​​A​​D​​F​​G​​L​​A​​K​973  ​L​​L​​P​​L​​D​​K​​D​​PTR​​PTR​​V​983  ​V​​R​​E​​P​​G​​Q​​S​​P​​I​​F​993  ​W​​Y​​A​​P​​E​​S​​L​​S​​D​​N​1003 ​I​​F​​S​​R​​Q​​S​​D​​V​​W​​S​1013 ​F​​G​​V​​V​​L​​Y​​E​​L​​F​​T​1023 ​Y​​C​​D​​K​​S​​C​​S​​P​​S​​A​1033 ​E​​F​​L​​R​​M​​M​​G​​S​​E​​R​     ​D​​V​​P​​A​​L​​S​​R​​L​​L​​E​1053 ​L​​L​​E​​E​​G​​Q​​R​​L​​P​​A​1063 ​P​​P​​A​​C​​P​​A​​E​​V​​H​​E​1073 ​L​​M​​K​​L​​C​​W​​A​​P​​S​​P​1083 ​Q​​D​​R​​P​​S​​F​​S​​A​​L​​G​1093 ​P​​Q​​L​​D​​M​​L​​W​​S​
Type
Asm Id
Dynamic Bonds

Select a different viewer

Citation:

See Citation Policies for referencing Mol*, RCSB PDB, PDB structures, and Computed Structure Models.