3D View: 3TZI

X-ray crystal structure of arachidonic acid bound in the cyclooxygenase channel of G533V murine COX-2

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RCSB PDB Mol* Viewer 2.10.6 [10/28/2024, 3:56:31 PM]
Sequence of
     ​A​​N​​H​​H​​H​​H​​H​​H​​P​​C​37   ​C​​S​​N​​P​​C​​Q​​N​​R​​G​​E​47   ​C​​M​​S​​T​​G​​F​​D​​Q​​Y​​K​57   ​C​​D​​C​​T​​R​​T​​G​​F​​Y​​G​67   ​E​​N​​C​​T​​T​​P​​E​​F​​L​​T​77   ​R​​I​​K​​L​​L​​L​​K​​P​​T​​P​87   ​N​​T​​V​​H​​Y​​I​​L​​T​​H​​F​97   ​K​​G​​V​​W​​N​​I​​V​​N​​N​​I​106  ​P​​F​​L​​R​​S​​L​​I​​M​​K​​Y​116  ​V​​L​​T​​S​​R​​S​​Y​​L​​I​​D​126  ​S​​P​​P​​T​​Y​​N​​V​​H​​Y​​G​136  ​Y​​K​​S​​W​​E​​A​​F​​S​​N​​L​146  ​S​​Y​​Y​​T​​R​​A​​L​​P​​P​​V​156  ​A​​D​​D​​C​​P​​T​​P​​M​​G​​V​166  ​K​​G​​N​​K​​E​​L​​P​​D​​S​​K​176  ​E​​V​​L​​E​​K​​V​​L​​L​​R​​R​186  ​E​​F​​I​​P​​D​​P​​Q​​G​​S​​N​196  ​M​​M​​F​​A​​F​​F​​A​​Q​​H​​F​206  ​T​​H​​Q​​F​​F​​K​​T​​D​​H​​K​216  ​R​​G​​P​​G​​F​​T​​R​​G​​L​​G​226  ​H​​G​​V​​D​​L​​N​​H​​I​​Y​​G​236  ​E​​T​​L​​D​​R​​Q​​H​​K​​L​​R​246  ​L​​F​​K​​D​​G​​K​​L​​K​​Y​​Q​256  ​V​​I​​G​​G​​E​​V​​Y​​P​​P​​T​266  ​V​​K​​D​​T​​Q​​V​​E​​M​​I​​Y​276  ​P​​P​​H​​I​​P​​E​​N​​L​​Q​​F​286  ​A​​V​​G​​Q​​E​​V​​F​​G​​L​​V​296  ​P​​G​​L​​M​​M​​Y​​A​​T​​I​​W​306  ​L​​R​​E​​H​​N​​R​​V​​C​​D​​I​316  ​L​​K​​Q​​E​​H​​P​​E​​W​​G​​D​326  ​E​​Q​​L​​F​​Q​​T​​S​​R​​L​​I​336  ​L​​I​​G​​E​​T​​I​​K​​I​​V​​I​346  ​E​​D​​Y​​V​​Q​​H​​L​​S​​G​​Y​356  ​H​​F​​K​​L​​K​​F​​D​​P​​E​​L​366  ​L​​F​​N​​Q​​Q​​F​​Q​​Y​​Q​​N​376  ​R​​I​​A​​S​​E​​F​​N​​T​​L​​Y​386  ​H​​W​​H​​P​​L​​L​​P​​D​​T​​F​396  ​N​​I​​E​​D​​Q​​E​​Y​​S​​F​​K​406  ​Q​​F​​L​​Y​​N​​N​​S​​I​​L​​L​416  ​E​​H​​G​​L​​T​​Q​​F​​V​​E​​S​426  ​F​​T​​R​​Q​​I​​A​​G​​R​​V​​A​436  ​G​​G​​R​​N​​V​​P​​I​​A​​V​​Q​446  ​A​​V​​A​​K​​A​​S​​I​​D​​Q​​S​456  ​R​​E​​M​​K​​Y​​Q​​S​​L​​N​​E​466  ​Y​​R​​K​​R​​F​​S​​L​​K​​P​​Y​476  ​T​​S​​F​​E​​E​​L​​T​​G​​E​​K​486  ​E​​M​​A​​A​​E​​L​​K​​A​​L​​Y​496  ​S​​D​​I​​D​​V​​M​​E​​L​​Y​​P​506  ​A​​L​​L​​V​​E​​K​​P​​R​​P​​D​516  ​A​​I​​F​​G​​E​​T​​M​​V​​E​​L​526  ​G​​A​​P​​F​​S​​L​​K​​V​​L​​M​536  ​G​​N​​P​​I​​C​​S​​P​​Q​​Y​​W​546  ​K​​P​​S​​T​​F​​G​​G​​E​​V​​G​556  ​F​​K​​I​​I​​N​​T​​A​​S​​I​​Q​566  ​S​​L​​I​​C​​N​​N​​V​​K​​G​​C​576  ​P​​F​​T​​S​​F​​N​​V​​Q​​D​​P​     ​Q​​P​​T​​K​​T​​A​​T​​I​​A​​A​     ​S​​A​​S​​H​​S​​R​​L​​D​​D​​I​     ​N​​P​​T​​V​​L​​I​​K​​R​​R​​S​     ​T​​E​​L​
Type
Asm Id
Dynamic Bonds

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