Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site

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RCSB PDB Mol* Viewer 2.11.2 [1/27/2025, 4:56:27 PM]
Sequence of
1    ​S​​L​​L​​E​​F​​G​​K​​M​​I​​L​11   ​E​​E​​T​​G​​K​​L​​A​​I​​P​​S​22   ​Y​​S​​S​​Y​​G​​C​​Y​​C​​G​​W​32   ​G​​G​​K​​G​​T​​P​​K​​D​​A​​T​42   ​D​​R​​C​​C​​F​​V​​H​​D​​C​​C​52   ​Y​​G​​N​​L​​P​​D​​C​​N​​P​​K​70   ​S​​D​​R​​Y​​K​​Y​​K​​R​​V​​N​80   ​G​​A​​I​​V​​C​​E​​K​​G​​T​​S​91   ​C​​E​​N​​R​​I​​C​​E​​C​​D​​K​101  ​A​​A​​A​​I​​C​​F​​R​​Q​​N​​L​111  ​N​​T​​Y​​S​​K​​K​​Y​​M​​L​​Y​121  ​P​​D​​F​​L​​C​​K​​G​​E​​L​​K​133  ​C​
Type
Asm Id
Dynamic Bonds

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